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PTK7 Produits

(PTK7 Protein tyrosine Kinase 7 (PTK7))

Catégories

This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012].

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Catégories PTK7 en vedette

PTK7 Anticorps

High quality antibodies with extensive validation data.

PTK7 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PTK7 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (1)
  • (3)
N° du produit ABIN392230
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
N° du produit ABIN519485
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (4)
N° du produit ABIN6146429
Quantité 100 μL
Fiche technique Fiche technique

PTK7 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6974488
Quantité 96 tests
Fiche technique Fiche technique

PTK7 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7274039
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7274040
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316785
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PTK7

Wang, Li, Yin, Wang, Wang, Wei, Guo, Ma, Shi, Zhou, Wang: "PTK7 protein is decreased in epithelial ovarian carcinomas with poor prognosis." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 11, pp. 7881-9, (2014) (PubMed).

Golubkov, Strongin: "Downstream signaling and genome-wide regulatory effects of PTK7 pseudokinase and its proteolytic fragments in cancer cells." dans: Cell communication and signaling : CCS, Vol. 12, pp. 15, (2014) (PubMed).

Golubkov, Prigozhina, Zhang, Stoletov, Lewis, Schwartz, Hoffman, Strongin: "Protein-tyrosine pseudokinase 7 (PTK7) directs cancer cell motility and metastasis." dans: The Journal of biological chemistry, Vol. 289, Issue 35, pp. 24238-49, (2014) (PubMed).

Chen, Khatri, Mazur, Polin, Zheng, Vaka, Hoang, Shrager, Xu, Vicent, Butte, Sweet-Cordero: "A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma." dans: Cancer research, Vol. 74, Issue 10, pp. 2892-902, (2014) (PubMed).

Golubkov, Chekanov, Cieplak, Aleshin, Chernov, Zhu, Radichev, Zhang, Dong, Strongin: "The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and embryogenesis." dans: The Journal of biological chemistry, Vol. 285, Issue 46, pp. 35740-9, (2010) (PubMed).

Haines, Giffon, Lu, Lu, Tessier-Lavigne, Ross, Lewis: "Human CD4+ T cell recent thymic emigrants are identified by protein tyrosine kinase 7 and have reduced immune function." dans: The Journal of experimental medicine, Vol. 206, Issue 2, pp. 275-85, (2009) (PubMed).

Shin, Maeng, Jung, Min, Kwon, Lee: "Soluble PTK7 inhibits tube formation, migration, and invasion of endothelial cells and angiogenesis." dans: Biochemical and biophysical research communications, Vol. 371, Issue 4, pp. 793-8, (2008) (PubMed).

Müller-Tidow, Schwäble, Steffen, Tidow, Brandt, Becker, Schulze-Bahr, Halfter, Vogt, Metzger, Schneider, Büchner, Brandts, Berdel, Serve: "High-throughput analysis of genome-wide receptor tyrosine kinase expression in human cancers identifies potential novel drug targets." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 4, pp. 1241-9, (2004) (PubMed).

Lu, Borchers, Jolicoeur, Rayburn, Baker, Tessier-Lavigne: "PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates." dans: Nature, Vol. 430, Issue 6995, pp. 93-8, (2004) (PubMed).

Zhang, Li, Martin, Aebersold: "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry." dans: Nature biotechnology, Vol. 21, Issue 6, pp. 660-6, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à PTK7

protein tyrosine kinase 7 (inactive) (PTK7), protein tyrosine kinase 7 (Ptk7), PTK7 protein tyrosine kinase 7 (Ptk7), 8430404F20Rik, CCK-4, CCK4, chz, KLG, mPTK7/CCK4, PTK7, Srf

Protein level used designations for PTK7

  • PTK7 protein tyrosine kinase 7
  • inactive tyrosine-protein kinase 7
  • tyrosine-protein kinase-like 7-like
  • colon carcinoma kinase 4
  • pseudo tyrosine kinase receptor 7
  • tyrosine-protein kinase-like 7
  • serum response factor
  • protein chuzhoi
  • protein-tyrosine kinase 7
  • receptor tyrosine kinase-like protein
  • kinase-like protein
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