PTP4A1 Produits
(Protein Tyrosine Phosphatase Type IVA, Member 1 (PTP4A1))
Catégories
The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. [provided by RefSeq, Jul 2008].
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Catégories PTP4A1 en vedette
PTP4A1 Anticorps
High quality antibodies with extensive validation data.
PTP4A1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PTP4A1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IF
Validations
- (2)
- (2)
N° du produit
ABIN185274
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB
Validations
- (2)
N° du produit
ABIN1536716
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, ICC
Validations
- (2)
N° du produit
ABIN6264513
Quantité
100 μL
Fiche technique
Fiche technique
PTP4A1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
N° du produit
ABIN7275477
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124677
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316799
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PTP4A1
: "New p53 target, phosphatase of regenerating liver 1 (PRL-1) downregulates p53." dans: Oncogene, Vol. 28, Issue 4, pp. 545-54, (2009) (PubMed).: "PRL-1 tyrosine phosphatase regulates c-Src levels, adherence, and invasion in human lung cancer cells." dans: Cancer research, Vol. 67, Issue 2, pp. 643-50, (2007) (PubMed).
: "Trimeric structure of PRL-1 phosphatase reveals an active enzyme conformation and regulation mechanisms." dans: Journal of molecular biology, Vol. 345, Issue 2, pp. 401-13, (2004) (PubMed).
: "Enhanced cell cycle progression and down regulation of p21(Cip1/Waf1) by PRL tyrosine phosphatases." dans: Cancer letters, Vol. 202, Issue 2, pp. 201-11, (2003) (PubMed).
: "The tyrosine phosphatase PRL-1 localizes to the endoplasmic reticulum and the mitotic spindle and is required for normal mitosis." dans: The Journal of biological chemistry, Vol. 277, Issue 48, pp. 46659-68, (2002) (PubMed).
: "The gene encoding human nuclear protein tyrosine phosphatase, PRL-1. Cloning, chromosomal localization, and identification of an intron enhancer." dans: The Journal of biological chemistry, Vol. 273, Issue 27, pp. 17286-95, (1998) (PubMed).
Synonymes et noms alternatifs relatifs à PTP4A1
protein tyrosine phosphatase type IVA, member 1 (PTP4A1), protein tyrosine phosphatase type IVA, member 1 L homeolog (ptp4a1.L), protein tyrosine phosphatase type IVA, member 1 (ptp4a1), protein tyrosine phosphatase type IVA, member 1 (Ptp4a1), protein tyrosine phosphatase 4a1 (Ptp4a1), AA415290, AU019864, C130021B01, DKFZp459E022, fb54d08, fc01c04, hh72, HH72, MGC79517, MGC83351, prl-1, PRL-1, Prl-1, prl1, PRL1, ptp(caax1), PTP(CAAX1), ptp4a1, Ptp4a1, PTP4A1, ptpcaax1, PTPCAAX1, wu:fb54d08, wu:fc01c04, zgc:101726Protein level used designations for PTP4A1
- protein tyrosine phosphatase type IVA 1
- protein tyrosine phosphatase type IVA, member 1
- PRL-1
- Protein tyrosine phosphatase type IVA 1
- protein-tyrosine phosphatase 4a1
- protein-tyrosine phosphatase of regenerating liver 1
- protein tyrosine phosphatase type IVA protein 1
- protein tyrosine phosphatase 4a1
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