PTP4A3 Produits
(Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
Catégories
The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. [provided by RefSeq, Jul 2008].
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Catégories PTP4A3 en vedette
PTP4A3 Anticorps
High quality antibodies with extensive validation data.
PTP4A3 Kits ELISA
Reliable ELISA kits for a wide range of species.
PTP4A3 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PTP4A3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (3)
N° du produit
ABIN7435550
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, ICC, IF
Validations
- (3)
N° du produit
ABIN6264515
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC
Validations
- (3)
N° du produit
ABIN1682391
Quantité
100 μg
Fiche technique
Fiche technique
PTP4A3 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958954
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4884249
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6384905
Quantité
96 tests
Fiche technique
Fiche technique
PTP4A3 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
N° du produit
ABIN7275479
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN666667
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316805
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PTP4A3
: "PRL-3 engages the focal adhesion pathway in triple-negative breast cancer cells to alter actin structure and substrate adhesion properties critical for cell migration and invasion." dans: Cancer letters, Vol. 380, Issue 2, pp. 505-12, (2016) (PubMed).: "Loss of the oncogenic phosphatase PRL-3 promotes a TNF-R1 feedback loop that mediates triple-negative breast cancer growth." dans: Oncogenesis, Vol. 5, Issue 8, pp. e255, (2016) (PubMed).
: "PRL-3 activates mTORC1 in Cancer Progression." dans: Scientific reports, Vol. 5, pp. 17046, (2015) (PubMed).
: "8q24 amplification is associated with Myc expression and prostate cancer progression and is an independent predictor of recurrence after radical prostatectomy." dans: Human pathology, Vol. 44, Issue 8, pp. 1617-23, (2013) (PubMed).
: "Overexpression and involvement in migration by the metastasis-associated phosphatase PRL-3 in human myeloma cells." dans: Blood, Vol. 111, Issue 2, pp. 806-15, (2008) (PubMed).
: "Structural insights into molecular function of the metastasis-associated phosphatase PRL-3." dans: The Journal of biological chemistry, Vol. 279, Issue 12, pp. 11882-9, (2004) (PubMed).
: "Structure of human PRL-3, the phosphatase associated with cancer metastasis." dans: FEBS letters, Vol. 565, Issue 1-3, pp. 181-7, (2004) (PubMed).
: "Phosphatase of regenerating liver-3 promotes motility and metastasis of mouse melanoma cells." dans: The American journal of pathology, Vol. 164, Issue 6, pp. 2039-54, (2004) (PubMed).
: "High expression of PRL-3 promotes cancer cell motility and liver metastasis in human colorectal cancer: a predictive molecular marker of metachronous liver and lung metastases." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 21, pp. 7318-28, (2004) (PubMed).
: "PRL-3 expression in metastatic cancers." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 9, Issue 15, pp. 5607-15, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à PTP4A3
protein tyrosine phosphatase type IVA, member 3 (PTP4A3), protein tyrosine phosphatase type IVA, member 3 (ptp4a3), protein tyrosine phosphatase type IVA, member 3 L homeolog (ptp4a3.L), protein tyrosine phosphatase 4a3 (Ptp4a3), protein tyrosine phosphatase type IVA, member 3 (Ptp4a3), AV088979, pPtp4a3, PRL-3, prl-3, Prl-3, PRL-R, PRL3, prl3, PTP4A3, ptpcaax3, wu:fc54b05, wu:fv52d11, zgc:77109Protein level used designations for PTP4A3
- potentially prenylated protein tyrosine phosphatase
- protein tyrosine phosphatase type IVA 3
- protein-tyrosine phosphatase 4a3
- protein-tyrosine phosphatase of regenerating liver 3
- PRL-3
- fc54b05
- fv52d11
- xPRL-3
- protein tyrosine phosphatase type IVA, member 3
- protein tyrosine phosphatase 4a3
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