PTPN21 Produits
(Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
Catégories
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq, Jul 2008].
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Catégories PTPN21 en vedette
PTPN21 Anticorps
High quality antibodies with extensive validation data.
PTPN21 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PTPN21 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (2)
N° du produit
ABIN392838
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (2)
N° du produit
ABIN7444973
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (2)
N° du produit
ABIN5014222
Quantité
100 μL
Fiche technique
Fiche technique
PTPN21 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7419742
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7419433
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3094803
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits PTPN21
: "BMX Negatively Regulates BAK Function, Thereby Increasing Apoptotic Resistance to Chemotherapeutic Drugs." dans: Cancer research, Vol. 75, Issue 7, pp. 1345-55, (2015) (PubMed).: "Protein-tyrosine phosphatase D1, a potential regulator and effector for Tec family kinases." dans: The Journal of biological chemistry, Vol. 275, Issue 52, pp. 41124-32, (2001) (PubMed).
: "Expression of protein tyrosine phosphatase PTP-RL10 and its isoform in the mouse testis." dans: International journal of urology : official journal of the Japanese Urological Association, Vol. 6, Issue 11, pp. 572-7, (2000) (PubMed).
Synonymes et noms alternatifs relatifs à PTPN21
protein tyrosine phosphatase, non-receptor type 21 (PTPN21), protein tyrosine phosphatase, non-receptor type 21 (Ptpn21), Ptp2E, PTPD1, PTPRL10Protein level used designations for PTPN21
- dJ1175B15.2 (protein tyrosine phosphatase, non-receptor type 21)
- protein tyrosine phosphatase D1
- protein-tyrosine phosphatase D1
- tyrosine-protein phosphatase non-receptor type 21
- protein-tyrosine phosphatase PTP-RL10
- protein tyrosine phosphatase 2E
- protein-tyrosine phosphatase 2E
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