PTPRF Produits
(Protein Tyrosine Phosphatase Receptor Type F (PTPRF))
Catégories
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008].
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Catégories PTPRF en vedette
PTPRF Anticorps
High quality antibodies with extensive validation data.
PTPRF Kits ELISA
Reliable ELISA kits for a wide range of species.
PTPRF Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PTPRF recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ICC, IHC, IP
Validations
- (4)
N° du produit
ABIN7444742
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, ICC, FACS, IHC, Neut
Validations
- (4)
N° du produit
ABIN7193270
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7167505
Quantité
100 μg
Fiche technique
Fiche technique
PTPRF recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969749
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958952
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6210120
Quantité
96 tests
Fiche technique
Fiche technique
PTPRF recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316869
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7418794
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PTPRF
: "A new 12-gene diagnostic biomarker signature of melanoma revealed by integrated microarray analysis." dans: PeerJ, Vol. 1, pp. e49, (2013) (PubMed).: "Trans-induced cis interaction in the tripartite NGL-1, netrin-G1 and LAR adhesion complex promotes development of excitatory synapses." dans: Journal of cell science, Vol. 126, Issue Pt 21, pp. 4926-38, (2013) (PubMed).
: "Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases." dans: The Journal of biological chemistry, Vol. 277, Issue 49, pp. 47263-9, (2002) (PubMed).
: "Regulation of Lck and Fyn tyrosine kinase activities by transmembrane protein tyrosine phosphatase leukocyte common antigen-related molecule." dans: Molecular cancer research : MCR, Vol. 1, Issue 2, pp. 155-63, (2002) (PubMed).
: "Galpha(i2) enhances insulin signaling via suppression of protein-tyrosine phosphatase 1B." dans: The Journal of biological chemistry, Vol. 276, Issue 43, pp. 39705-12, (2001) (PubMed).
: "Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 9, pp. 5187-92, (2001) (PubMed).
: "Use of an antisense strategy to dissect the signaling role of protein-tyrosine phosphatase alpha." dans: The Journal of biological chemistry, Vol. 274, Issue 37, pp. 26105-12, (1999) (PubMed).
: "Leukocyte common antigen-related receptor-linked tyrosine phosphatase. Regulation of mRNA expression." dans: The Journal of biological chemistry, Vol. 268, Issue 35, pp. 26503-11, (1994) (PubMed).
: "The SJL/J T cell response to both spontaneous and transplantable syngeneic reticulum cell sarcoma is mediated predominantly by the V beta 17a+ T cell clonotype." dans: The Journal of experimental medicine, Vol. 168, Issue 5, pp. 1553-62, (1988) (PubMed).
Synonymes et noms alternatifs relatifs à PTPRF
protein tyrosine phosphatase, receptor type F (PTPRF), protein tyrosine phosphatase, receptor type, F (Ptprf), protein tyrosine phosphatase, receptor type, f, a (ptprfa), AA591035, LAR, LARFN5C, LARS, RPTP-LAR, zf-LARProtein level used designations for PTPRF
- LCA-homolog
- leukocyte antigen-related (LAR) PTP receptor
- leukocyte antigen-related tyrosine phosphatase
- leukocyte common antigen related
- protein tyrosine phosphatase, receptor type, F polypeptide
- receptor-linked protein-tyrosine phosphatase LAR
- receptor-type tyrosine-protein phosphatase F
- LAR
- protein tyrosine phosphatase receptor-type F
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