PTPRN Produits
(Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
Catégories
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010].
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Catégories PTPRN en vedette
PTPRN Anticorps
High quality antibodies with extensive validation data.
PTPRN Kits ELISA
Reliable ELISA kits for a wide range of species.
PTPRN Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PTPRN recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), IHC (fro), ICC
Validations
- (3)
N° du produit
ABIN7439915
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
N° du produit
ABIN948357
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), IHC (fro), ICC
Validations
- (2)
N° du produit
ABIN7444055
Quantité
100 μL
Fiche technique
Fiche technique
PTPRN recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962149
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969757
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969756
Quantité
96 tests
Fiche technique
Fiche technique
PTPRN recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124688
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124687
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316877
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PTPRN
: "Small cell lung cancer growth is inhibited by miR-342 through its effect of the target gene IA-2." dans: Journal of translational medicine, Vol. 14, Issue 1, pp. 278, (2016) (PubMed).: "Novel pancreatic beta cell-specific proteins: antibody-based proteomics for identification of new biomarker candidates." dans: Journal of proteomics, Vol. 75, Issue 9, pp. 2611-20, (2012) (PubMed).
: "Structure of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase IA-2." dans: The Journal of biological chemistry, Vol. 283, Issue 8, pp. 4674-81, (2008) (PubMed).
: "ICA512 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATs." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 2, pp. 674-9, (2008) (PubMed).
: "RESP18, a homolog of the luminal domain IA-2, is found in dense core vesicles in pancreatic islet cells and is induced by high glucose." dans: The Journal of endocrinology, Vol. 195, Issue 2, pp. 313-21, (2007) (PubMed).
: "High titer of autoantibodies to GAD identifies a specific phenotype of adult-onset autoimmune diabetes." dans: Diabetes Care, Vol. 30, Issue 4, pp. 932-8, (2007) (PubMed).
: "ICA512(IA-2) epitope specific assays distinguish transient from diabetes associated autoantibodies." dans: Journal of autoimmunity, Vol. 18, Issue 2, pp. 191-6, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à PTPRN
protein tyrosine phosphatase, receptor type N (PTPRN), protein tyrosine phosphatase, receptor type, N (Ptprn), protein tyrosine phosphatase, receptor type N (Ptprn), protein tyrosine phosphatase, receptor type, Na (ptprna), protein tyrosine phosphatase, receptor type N L homeolog (ptprn.L), fc43c04, IA-2, Ia-2, ia-2, IA-2/PTP, IA2, ia2, ICA512, ica512, mIA-A, mKIAA4064, ptprn, R-PTP-N, r-ptp-n, wu:fc43c04Protein level used designations for PTPRN
- ICA 512
- PTP IA-2
- islet cell antigen 2
- islet cell antigen 512
- islet cell autoantigen 3
- protein tyrosine phosphatase-like N
- receptor-type tyrosine-protein phosphatase-like N
- ICA512
- R-PTP-N
- islet cell autoantigen 512
- protein tyrosine phosphatase, receptor-type, N
- 105 kDa islet cell antigen
- BEM-3
- ICA105
- PTPLP
- brain-enriched membrane-associated protein tyrosine phosphatase
- insulinoma antigen-2
- receptor type N protein tyrosine phosphatase
- protein tyrosine phosphatase, receptor type, N
- protein tyrosine phosphatase, receptor type, Na
- protein tyrosine phosphatase, receptor type N L homeolog
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