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PUM2 Produits

(Pumilio Homolog 2 (Drosophila) (PUM2))

Catégories

Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts (By similarity).

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Catégories PUM2 en vedette

PUM2 Anticorps

High quality antibodies with extensive validation data.

PUM2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PUM2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (3)
N° du produit ABIN392131
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN185369
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
N° du produit ABIN391821
Quantité 400 μL
Fiche technique Fiche technique

PUM2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6231949
Quantité 96 tests
Fiche technique Fiche technique

PUM2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316915
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3094816
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3136013
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits PUM2

Valluy, Bicker, Aksoy-Aksel, Lackinger, Sumer, Fiore, Wüst, Seffer, Metge, Dieterich, Wöhr, Schwarting, Schratt: "A coding-independent function of an alternative Ube3a transcript during neuronal development." dans: Nature neuroscience, Vol. 18, Issue 5, pp. 666-73, (2015) (PubMed).

Fiore, Rajman, Schwale, Bicker, Antoniou, Bruehl, Draguhn, Schratt: "MiR-134-dependent regulation of Pumilio-2 is necessary for homeostatic synaptic depression." dans: The EMBO journal, Vol. 33, Issue 19, pp. 2231-46, (2014) (PubMed).

Friend, Brook, Bezirci, Sheets, Gray, Seli: "Embryonic poly(A)-binding protein (ePAB) phosphorylation is required for Xenopus oocyte maturation." dans: The Biochemical journal, Vol. 445, Issue 1, pp. 93-100, (2012) (PubMed).

Marrero, Rossi, Darr, Tsoulfas, Rotundo: "Translational regulation of acetylcholinesterase by the RNA-binding protein Pumilio-2 at the neuromuscular synapse." dans: The Journal of biological chemistry, Vol. 286, Issue 42, pp. 36492-9, (2011) (PubMed).

Christensen, Larsen, Kauppinen, Schratt: "Recombinant Adeno-Associated Virus-Mediated microRNA Delivery into the Postnatal Mouse Brain Reveals a Role for miR-134 in Dendritogenesis in Vivo." dans: Frontiers in neural circuits, Vol. 3, pp. 16, (2010) (PubMed).

Kusz, Ginter-Matuszewska, Ziolkowska, Spik, Bierla, Jedrzejczak, Latos-Bielenska, Pawelczyk, Jaruzelska: "Polymorphisms of the human PUMILIO2 gene and male sterility." dans: Molecular reproduction and development, Vol. 74, Issue 6, pp. 795-9, (2007) (PubMed).

Spik, Oczkowski, Olszak, Kotecki, Formanowicz, B?azewicz, Jaruzelska: "Candidate mRNAs interacting with fertility protein PUMILIO2 in the human germ line." dans: Reproductive biology, Vol. 6 Suppl 1, pp. 37-42, (2006) (PubMed).

Padmanabhan, Richter: "Regulated Pumilio-2 binding controls RINGO/Spy mRNA translation and CPEB activation." dans: Genes & development, Vol. 20, Issue 2, pp. 199-209, (2006) (PubMed).

Szakmary, Cox, Wang, Lin: "Regulatory relationship among piwi, pumilio, and bag-of-marbles in Drosophila germline stem cell self-renewal and differentiation." dans: Current biology : CB, Vol. 15, Issue 2, pp. 171-8, (2005) (PubMed).

Masutomi, Possemato, Wong, Currier, Tothova, Manola, Ganesan, Lansdorp, Collins, Hahn: "The telomerase reverse transcriptase regulates chromatin state and DNA damage responses." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 23, pp. 8222-7, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à PUM2

pumilio RNA binding family member 2 (pum2), pumilio RNA-binding family member 2 (Pum2), pumilio RNA binding family member 2 (PUM2), 5730503J23Rik, mKIAA0235, pum-2, PUMH2, PUML2, Pumm2

Protein level used designations for PUM2

  • pumilio-2
  • PUM1
  • pumilio homolog 2
  • pumilio 2
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