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PVRL2 Produits

(Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Catégories

This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

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Catégories PVRL2 en vedette

PVRL2 Anticorps

High quality antibodies with extensive validation data.

PVRL2 Kits ELISA

Reliable ELISA kits for a wide range of species.

PVRL2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PVRL2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7441772
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application FACS, ELISA
Validations
  • (4)
N° du produit ABIN5611344
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IP
Validations
  • (4)
N° du produit ABIN562545
Quantité 100 μg
Fiche technique Fiche technique

PVRL2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969439
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1116602
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4883871
Quantité 96 tests
Fiche technique Fiche technique

PVRL2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
N° du produit ABIN7275309
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7275317
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275305
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PVRL2

Du, de Almeida, Manieri, de Almeida Nagata, Wu, Harden Bowles, Arumugam, Schartner, Cubas, Mittman, Javinal, Anderson, Warming, Grogan, Chiang: "CD226 regulates natural killer cell antitumor responses via phosphorylation-mediated inactivation of transcription factor FOXO1." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 50, pp. E11731-E11740, (2019) (PubMed).

Ott, Avendaño-Guzmán, Ullrich, Dreyer, Strauss, Harden, Schön, Schön, Bernhardt, Stadelmann, Wegner, Brück, Nessler: "Laquinimod, a prototypic quinoline-3-carboxamide and aryl hydrocarbon receptor agonist, utilizes a CD155-mediated natural killer/dendritic cell interaction to suppress CNS autoimmunity." dans: Journal of neuroinflammation, Vol. 16, Issue 1, pp. 49, (2019) (PubMed).

Molfetta, Milito, Zitti, Lecce, Fionda, Cippitelli, Santoni, Paolini: "The Ubiquitin-proteasome pathway regulates Nectin2/CD112 expression and impairs NK cell recognition and killing." dans: European journal of immunology, Vol. 49, Issue 6, pp. 873-883, (2019) (PubMed).

Tremblay-McLean, Coenraads, Kiani, Dupuy, Bernard: "Expression of ligands for activating natural killer cell receptors on cell lines commonly used to assess natural killer cell function." dans: BMC immunology, Vol. 20, Issue 1, pp. 8, (2019) (PubMed).

Bekes, Löb, Holzheu, Janni, Baumann, Wöckel, Wulff: "Nectin-2 in ovarian cancer: How is it expressed and what might be its functional role?" dans: Cancer science, Vol. 110, Issue 6, pp. 1872-1882, (2019) (PubMed).

Nakamura, Miyagawa, Yoshida, Sasawatari, Toyofuku, Toda, Sawa: "Natural killer cells impede the engraftment of cardiomyocytes derived from induced pluripotent stem cells in syngeneic mouse model." dans: Scientific reports, Vol. 9, Issue 1, pp. 10840, (2019) (PubMed).

Josifovska, Szabó, Nagymihály, Veréb, Facskó, Eriksen, Moe, Petrovski: "Cultivation and characterization of pterygium as an ex vivo study model for disease and therapy." dans: Contact lens & anterior eye : the journal of the British Contact Lens Association, Vol. 40, Issue 5, pp. 283-292, (2018) (PubMed).

Zhang, Bi, Zheng, Chen, Wang, Wu, Wang, Wu, Peng, Wei, Sun, Tian: "Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity." dans: Nature immunology, Vol. 19, Issue 7, pp. 723-732, (2018) (PubMed).

Walwyn-Brown, Guldevall, Saeed, Pende, Önfelt, MacDonald, Davis: "Human NK Cells Lyse Th2-Polarizing Dendritic Cells via NKp30 and DNAM-1." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 201, Issue 7, pp. 2028-2041, (2018) (PubMed).

Zitti, Molfetta, Fionda, Quatrini, Stabile, Lecce, de Turris, Ricciardi, Petrucci, Cippitelli, Gismondi, Santoni, Paolini: "Innate immune activating ligand SUMOylation affects tumor cell recognition by NK cells." dans: Scientific reports, Vol. 7, Issue 1, pp. 10445, (2017) (PubMed).

Synonymes et noms alternatifs relatifs à PVRL2

nectin cell adhesion molecule 2 (Nectin2), nectin cell adhesion molecule 2 (NECTIN2), AI325026, AI987993, Cd112, CD112, HVEB, MPH, nectin-2, prr2, PRR2, Pvr, PVRR2, Pvs

Protein level used designations for PVRL2

  • poliovirus receptor-related protein 2
  • herpes virus entry mediator B
  • herpesvirus entry mediator B
  • hveB
  • mHveB
  • murine herpes virus entry protein B
  • murine herpesvirus entry protein B
  • poliovirus receptor homolog
  • poliovirus sensitivity
  • nectin-2
  • poliovirus receptor related 2
  • poliovirus receptor-related 2 (herpesvirus entry mediator B)
  • herpesvirus entry protein B
  • poliovirus receptor-like 2
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