PYCARD Produits
(PYD and CARD Domain Containing (PYCARD))
Catégories
This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm\; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories PYCARD en vedette
PYCARD Anticorps
High quality antibodies with extensive validation data.
PYCARD Kits ELISA
Reliable ELISA kits for a wide range of species.
PYCARD Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PYCARD recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (7)
N° du produit
ABIN6146515
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (1)
- (7)
N° du produit
ABIN3021617
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC, FACS, ICC
Validations
- (7)
N° du produit
ABIN5542580
Quantité
100 μL
Fiche technique
Fiche technique
PYCARD recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969788
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969787
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6976147
Quantité
96 tests
Fiche technique
Fiche technique
PYCARD recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1316968
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3089316
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3137154
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits PYCARD
: "PM2.5 exposure impairs sperm quality through testicular damage dependent on NALP3 inflammasome and miR-183/96/182 cluster targeting FOXO1 in mouse." dans: Ecotoxicology and environmental safety, Vol. 169, pp. 551-563, (2019) (PubMed).: "AIM2 gene silencing attenuates diabetic cardiomyopathy in type 2 diabetic rat model." dans: Life sciences, Vol. 221, pp. 249-258, (2019) (PubMed).
: "Evaluation of Canonical Inflammasome Activation in Human Monocytes by Imaging Flow Cytometry." dans: Frontiers in immunology, Vol. 10, pp. 1284, (2019) (PubMed).
: "NLRP3 inflammasome activation in platelets in response to sepsis." dans: Physiological reports, Vol. 7, Issue 9, pp. e14073, (2019) (PubMed).
: "Ozone protects the rat lung from ischemia-reperfusion injury by attenuating NLRP3-mediated inflammation, enhancing Nrf2 antioxidant activity and inhibiting apoptosis." dans: European journal of pharmacology, Vol. 835, pp. 82-93, (2018) (PubMed).
: "Oral Administration of Compound Probiotics Ameliorates HFD-Induced Gut Microbe Dysbiosis and Chronic Metabolic Inflammation via the G Protein-Coupled Receptor 43 in Non-alcoholic Fatty Liver Disease ..." dans: Probiotics and antimicrobial proteins, (2018) (PubMed).
: "S. aureus Evades Macrophage Killing through NLRP3-Dependent Effects on Mitochondrial Trafficking." dans: Cell reports, Vol. 22, Issue 9, pp. 2431-2441, (2018) (PubMed).
: "NLRP3 inflammasome expression in lipopolysaccharide-induced otitis media." dans: Acta oto-laryngologica, Vol. 138, Issue 12, pp. 1061-1065, (2018) (PubMed).
: "Actin polymerization plays a significant role in asbestos-induced inflammasome activation in mesothelial cells in vitro." dans: Histochemistry and cell biology, Vol. 147, Issue 5, pp. 595-604, (2018) (PubMed).
: "Human Parvovirus Infection of Human Airway Epithelia Induces Pyroptotic Cell Death by Inhibiting Apoptosis." dans: Journal of virology, Vol. 91, Issue 24, (2017) (PubMed).
Synonymes et noms alternatifs relatifs à PYCARD
PYD and CARD domain containing (PYCARD), PYD and CARD domain containing (Pycard), PYD and CARD domain containing (pycard), 9130417A21Rik, ASC, Asc, asc1, CARD5, masc, TMS, TMS-1, TMS1, TNS1, zAsc, zgc:109874Protein level used designations for PYCARD
- apoptosis-associated speck-like protein containing a CARD
- caspase recruitment domain-containing protein 5
- target of methylation-induced silencing 1
- PYD and CARD domain-containing protein
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