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PYM Produits

(Partner of Y14 and mago (WIBG))

Catégories

Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post- transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as a EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions (By similarity).

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Catégories PYM en vedette

PYM Anticorps

High quality antibodies with extensive validation data.

PYM Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PYM recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
N° du produit ABIN654666
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB
Validations
  • (1)
N° du produit ABIN6750448
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Bat, Cow, Dog, Horse, Human, Monkey, Pig, Xenopus laevis
Application WB
Validations
  • (1)
N° du produit ABIN6746847
Quantité 100 μL
Fiche technique Fiche technique

PYM recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1325328
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN1097293
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2132576
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PYM

Li, Johnson, Truong, Kim, Weinbren, Dittmar, Shah, Von Dollen, Newton, Jang, Krogan, Cherry, Ramage: "Identification of antiviral roles for the exon-junction complex and nonsense-mediated decay in flaviviral infection." dans: Nature microbiology, Vol. 4, Issue 6, pp. 985-995, (2019) (PubMed).

Sun, Boxer, Ransohoff, Siprashvili, Qu, Lopez-Pajares, Hollmig, Khavari: "CALML5 is a ZNF750- and TINCR-induced protein that binds stratifin to regulate epidermal differentiation." dans: Genes & development, Vol. 29, Issue 21, pp. 2225-30, (2015) (PubMed).

Synonymes et noms alternatifs relatifs à PYM

Partner of Y14 and Mago (Pym), Wibg protein (wibg), PYM homolog 1, exon junction complex associated factor L homeolog (pym1.L), PYM homolog 1, exon junction complex associated factor (PYM1), PYM homolog 1, exon junction complex associated factor (Pym1), PYM homolog 1, exon junction complex associated factor (pym1), A030010B05Rik, BEST:HL05757, CG10330, CG30176, Dmel\\CG30176, PYM, Pym, UD3, zgc:65891, zgc:77281

Protein level used designations for PYM

  • CG30176-PA
  • undefined 3
  • wibg-PA
  • Protein wibg homolog
  • partner of Y14 and mago
  • protein wibg homolog
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