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RAB7A Produits

(RAB7A, Member RAS Oncogene Family (RAB7A))

Catégories

RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008].

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Catégories RAB7A en vedette

RAB7A Anticorps

High quality antibodies with extensive validation data.

RAB7A Kits ELISA

Reliable ELISA kits for a wide range of species.

RAB7A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

RAB7A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC (p), FACS
Validations
  • (7)
N° du produit ABIN652609
Quantité 400 μL
Fiche technique Fiche technique

Application WB, IF
Validations
  • (5)
N° du produit ABIN6254195
Quantité 600 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IF (cc)
Validations
  • (1)
  • (3)
N° du produit ABIN720191
Quantité 100 μL
Fiche technique Fiche technique

RAB7A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959032
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6951224
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5658345
Quantité 96 tests
Fiche technique Fiche technique

RAB7A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124764
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1317193
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7321067
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits RAB7A

Pohar, Lainšček, Ivičak-Kocjan, Cajnko, Jerala, Benčina: "Short single-stranded DNA degradation products augment the activation of Toll-like receptor 9." dans: Nature communications, Vol. 8, pp. 15363, (2018) (PubMed).

Pera, Larrea, Guardia-Laguarta, Montesinos, Velasco, Agrawal, Xu, Chan, Di Paolo, Mehler, Perumal, Macaluso, Freyberg, Acin-Perez, Enriquez, Schon, Area-Gomez: "Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease." dans: The EMBO journal, Vol. 36, Issue 22, pp. 3356-3371, (2017) (PubMed).

Mascia, Gentile, Izzo, Mollo, De Luca, Bucci, Nitsch, Calì: "Rab7 Regulates CDH1 Endocytosis, Circular Dorsal Ruffles Genesis, and Thyroglobulin Internalization in a Thyroid Cell Line." dans: Journal of cellular physiology, Vol. 231, Issue 8, pp. 1695-708, (2016) (PubMed).

Aboul Naga, Dithmer, Chitadze, Kabelitz, Lucius, Roider, Klettner: "Intracellular pathways following uptake of bevacizumab in RPE cells." dans: Experimental eye research, Vol. 131, pp. 29-41, (2015) (PubMed).

Zhuang, Northup, Ray: "Large putative PEST-like sequence motif at the carboxyl tail of human calcium receptor directs lysosomal degradation and regulates cell surface receptor level." dans: The Journal of biological chemistry, Vol. 287, Issue 6, pp. 4165-76, (2012) (PubMed).

Ye, Gao, Tian, Yearsley, Lange, Robertson, Barsky: "Early to intermediate steps of tumor embolic formation involve specific proteolytic processing of E-cadherin regulated by Rab7." dans: Molecular cancer research : MCR, Vol. 10, Issue 6, pp. 713-26, (2012) (PubMed).

Cheng, Shih, Huang, Chi, Wu, Liu: "Bovine ephemeral fever virus uses a clathrin-mediated and dynamin 2-dependent endocytosis pathway that requires Rab5 and Rab7 as well as microtubules." dans: Journal of virology, Vol. 86, Issue 24, pp. 13653-61, (2012) (PubMed).

Meggouh, Bienfait, Weterman, de Visser, Baas: "Charcot-Marie-Tooth disease due to a de novo mutation of the RAB7 gene." dans: Neurology, Vol. 67, Issue 8, pp. 1476-8, (2006) (PubMed).

Wu, Wang, Loh, Hong, Song: "Structural basis for recruitment of RILP by small GTPase Rab7." dans: The EMBO journal, Vol. 24, Issue 8, pp. 1491-501, (2005) (PubMed).

Verhoeven, De Jonghe, Coen, Verpoorten, Auer-Grumbach, Kwon, FitzPatrick, Schmedding, De Vriendt, Jacobs, Van Gerwen, Wagner, Hartung, Timmerman: "Mutations in the small GTP-ase late endosomal protein RAB7 cause Charcot-Marie-Tooth type 2B neuropathy." dans: American journal of human genetics, Vol. 72, Issue 3, pp. 722-7, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à RAB7A

RAB5A, member RAS oncogene family (RAB5A), RAB7A, member RAS oncogene family (RAB7A), RAB7A, member RAS oncogene family (Rab7a), RAB7A, member RAS oncogene family L homeolog (rab7a.L), RAB7A, member RAS oncogene family (rab7a), rab7A protein (rab7A), RAB GTPase homolog 7A (RAB7A), Rab GTPase (rab7A), ras-related protein rab-7a (rab7a), RAB7, member RAS oncogene family (Rab7), RAB7, member RAS oncogene family (rab7), ARABIDOPSIS RAB GTPASE HOMOLOG G2, ATRAB7A, ATRABG2, DDBDRAFT_0190210, DDBDRAFT_0191507, DDB_0190210, DDB_0191507, F7D8.20, F7D8_20, LOC100231734, PRO2706, pro2706, rab-7, RAB5, RAB7, Rab7, rab7, RAB7A, Rab7a, RAB GTPase homolog 7A, zgc:64058

Protein level used designations for RAB7A

  • RAS-associated protein RAB5A
  • ras-related protein Rab-5A
  • RAB7, member RAS oncogene family
  • Ras-associated protein RAB7
  • ras-related protein Rab-7a
  • ras-related protein BRL-RAS
  • ras-related protein p23
  • GTP-binding protein (rab7)
  • ras-related protein Rab-7
  • RAB7A, member RAS oncogene family
  • rab7A protein
  • ras-related protein rab-7a
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