RAB8A Produits
(RAB8A, Member RAS Oncogene Family (RAB8A))
Catégories
The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. [provided by RefSeq, Jul 2008].
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Catégories RAB8A en vedette
RAB8A Anticorps
High quality antibodies with extensive validation data.
RAB8A Kits ELISA
Reliable ELISA kits for a wide range of species.
RAB8A Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
RAB8A recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (2)
- (4)
N° du produit
ABIN1881723
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
N° du produit
ABIN5542342
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
N° du produit
ABIN561805
Quantité
100 μg
Fiche technique
Fiche technique
RAB8A recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969818
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Validations
N° du produit
ABIN1154795
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Cow
Analytical Method
Validations
N° du produit
ABIN1154790
Quantité
96 tests
Fiche technique
Fiche technique
RAB8A recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1317201
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1317203
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2730373
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits RAB8A
: "Transcription factor EB‑mediated autophagy promotes dermal fibroblast differentiation and collagen production by regulating endoplasmic reticulum stress and autophagy‑dependent secretion." dans: International journal of molecular medicine, Vol. 47, Issue 2, pp. 547-560, (2021) (PubMed).: "Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3." dans: The Journal of cell biology, Vol. 211, Issue 3, pp. 587-604, (2015) (PubMed).
: "Drebrin E depletion in human intestinal epithelial cells mimics Rab8a loss of function." dans: Human molecular genetics, Vol. 23, Issue 11, pp. 2834-46, (2014) (PubMed).
: "Levels of Rabs and WAVE family proteins associated with translocation of GLUT4 to the cell surface in endometria from hyperinsulinemic PCOS women." dans: Human reproduction (Oxford, England), Vol. 25, Issue 11, pp. 2870-7, (2010) (PubMed).
: "Functional dissection of Rab GTPases involved in primary cilium formation." dans: The Journal of cell biology, Vol. 178, Issue 3, pp. 363-9, (2007) (PubMed).
: "Rab27a: A key to melanosome transport in human melanocytes." dans: The Journal of cell biology, Vol. 152, Issue 4, pp. 843-50, (2001) (PubMed).
: "Rab27a regulates the peripheral distribution of melanosomes in melanocytes." dans: The Journal of cell biology, Vol. 152, Issue 4, pp. 795-808, (2001) (PubMed).
: "Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation." dans: Molecular biology of the cell, Vol. 11, Issue 1, pp. 393-412, (2000) (PubMed).
: "Construction of a human full-length cDNA bank." dans: Gene, Vol. 150, Issue 2, pp. 243-50, (1995) (PubMed).
: "A small rab GTPase is distributed in cytoplasmic vesicles in non polarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells." dans: The Journal of cell biology, Vol. 124, Issue 1-2, pp. 101-15, (1994) (PubMed).
Synonymes et noms alternatifs relatifs à RAB8A
rab8A protein (rab8A), Rab GTPase (rab8A), RAB8A, member RAS oncogene family (RAB8A), RAB8A, member RAS oncogene family (rab8a), RAB8A, member RAS oncogene family S homeolog (rab8a.S), RAB8A, member RAS oncogene family (Rab8a), AA409338, c-mel, DDBDRAFT_0206521, DDBDRAFT_0214885, DDB_0206521, DDB_0214885, HSH2D, mel, MEL, Mel, rab8, RAB8, Rab8, rab8A, zgc:162699Protein level used designations for RAB8A
- rab8A protein
- hematopoietic SH2 domain containing
- ras-related protein Rab-8A
- RAB8A, member RAS oncogene family
- member RAS oncogene family
- Ras-related protein Rab-8A
- mel transforming oncogene (RAB8 homolog)
- mel transforming oncogene (derived from cell line NK14)
- mel transforming oncogene (derived from cell line NK14)- RAB8 homolog
- oncogene c-mel
- ras-associated protein RAB8
- RAB8, member RAS oncogene family
- cell line NK14 derived transforming oncogene
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