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RAD51 Homolog B Produits

(RAD51 Homolog B (Rad51B))

Catégories

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Jul 2011].

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Catégories RAD51 Homolog B en vedette

RAD51 Homolog B Anticorps

High quality antibodies with extensive validation data.

RAD51 Homolog B Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

RAD51 Homolog B recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Monkey, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
N° du produit ABIN6259179
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (4)
N° du produit ABIN2787357
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (2)
N° du produit ABIN2565838
Quantité 50 μg
Fiche technique Fiche technique

RAD51 Homolog B recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6232260
Quantité 96 tests
Fiche technique Fiche technique

RAD51 Homolog B recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1317287
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2131471
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3094872
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits RAD51 Homolog B

Jensen, Ozes, Kim, Estep, Kowalczykowski: "BRCA2 is epistatic to the RAD51 paralogs in response to DNA damage." dans: DNA repair, Vol. 12, Issue 4, pp. 306-11, (2013) (PubMed).

Bossy, Petrilli, Klinglmayr, Chen, Lütz-Meindl, Knott, Masliah, Schwarzenbacher, Bossy-Wetzel: "S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease." dans: Journal of Alzheimer's disease : JAD, Vol. 20 Suppl 2, Issue 6, pp. S513-26, (2010) (PubMed).

Shammas, Shmookler Reis, Koley, Batchu, Li, Munshi: "Dysfunctional homologous recombination mediates genomic instability and progression in myeloma." dans: Blood, Vol. 113, Issue 10, pp. 2290-7, (2009) (PubMed).

Nagaraju, Odate, Xie, Scully: "Differential regulation of short- and long-tract gene conversion between sister chromatids by Rad51C." dans: Molecular and cellular biology, Vol. 26, Issue 21, pp. 8075-86, (2006) (PubMed).

Lambert, Lopez: "Inactivation of the RAD51 recombination pathway stimulates UV-induced mutagenesis in mammalian cells." dans: Oncogene, Vol. 21, Issue 25, pp. 4065-9, (2002) (PubMed).

Masson, Tarsounas, Stasiak, Stasiak, Shah, McIlwraith, Benson, West: "Identification and purification of two distinct complexes containing the five RAD51 paralogs." dans: Genes & development, Vol. 15, Issue 24, pp. 3296-307, (2001) (PubMed).

Albala, Thelen, Prange, Fan, Christensen, Thompson, Lennon: "Identification of a novel human RAD51 homolog, RAD51B." dans: Genomics, Vol. 46, Issue 3, pp. 476-9, (1998) (PubMed).

Synonymes et noms alternatifs relatifs à RAD51 Homolog B

RAD51 paralog B (RAD51B), RAD51 paralog B (Rad51b), DNA repair (Rad51) family protein (RAD51B), Rad51 DNA recombinase 2 (RAD51B), RAD51 paralog B (rad51b), AI553500, ATRAD51B, mREC2, R51H2, RAD51L1, Rad51l1, rad51l1, REC2, RGD1560681, T17D12.12, T17D12_12, wu:fd07f04, zgc:56581

Protein level used designations for RAD51 Homolog B

  • DNA repair protein RAD51 homolog 2
  • RAD51 homolog B
  • RecA-like protein
  • recombination repair protein
  • RAD51-like 1
  • RAD51-like protein 1
  • Rad51 DNA recombinase 2
  • DKEYP-88E3.2
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