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RAP1A Produits

(RAP1A, Member of RAS Oncogene Family (RAP1A))
The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].

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Catégories RAP1A en vedette

RAP1A Anticorps

High quality antibodies with extensive validation data.

RAP1A Kits ELISA

Reliable ELISA kits for a wide range of species.

RAP1A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

RAP1A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, FACS
Validations
  • (2)
  • (4)
N° du produit ABIN969561
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
N° du produit ABIN3021200
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, PLA
Validations
  • (1)
  • (3)
N° du produit ABIN519632
Quantité 100 μg
Fiche technique Fiche technique

RAP1A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969828
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969827
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969829
Quantité 96 tests
Fiche technique Fiche technique

RAP1A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
N° du produit ABIN1317390
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124776
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2131496
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits RAP1A

Chinigò, Grolez, Audero, Bokhobza, Bernardini, Cicero, Toillon, Bailleul, Visentin, Ruffinatti, Brysbaert, Lensink, De Ruyck, Cantelmo, Fiorio Pla, Gkika: "TRPM8-Rap1A Interaction Sites as Critical Determinants for Adhesion and Migration of Prostate and Other Epithelial Cancer Cells." dans: Cancers, Vol. 14, Issue 9, (2022) (PubMed).

Stott, Barrese, Suresh, Masoodi, Greenwood: "Investigating the Role of G Protein βγ in Kv7-Dependent Relaxations of the Rat Vasculature." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 38, Issue 9, pp. 2091-2102, (2019) (PubMed).

Chen, Chuang, Huang, Fang, Huang, Tsai, Su, Shiu, Leu, Chien: "Overexpression of Rap-1A indicates a poor prognosis for oral cavity squamous cell carcinoma and promotes tumor cell invasion via Aurora-A modulation." dans: The American journal of pathology, Vol. 182, Issue 2, pp. 516-28, (2013) (PubMed).

Severson, Lee, Capaldo, Nusrat, Parkos: "Junctional adhesion molecule A interacts with Afadin and PDZ-GEF2 to activate Rap1A, regulate beta1 integrin levels, and enhance cell migration." dans: Molecular biology of the cell, Vol. 20, Issue 7, pp. 1916-25, (2009) (PubMed).

Dao, Dupuy, Gavet, Caron, de Gunzburg: "Dynamic changes in Rap1 activity are required for cell retraction and spreading during mitosis." dans: Journal of cell science, Vol. 122, Issue Pt 16, pp. 2996-3004, (2009) (PubMed).

Branham, Bustos, De Blas, Rehmann, Zarelli, Treviño, Darszon, Mayorga, Tomes: "Epac activates the small G proteins Rap1 and Rab3A to achieve exocytosis." dans: The Journal of biological chemistry, Vol. 284, Issue 37, pp. 24825-39, (2009) (PubMed).

Chu, Awasthi, White, Chrzanowska-Wodnicka, Malarkannan: "Rap1b regulates B cell development, homing, and T cell-dependent humoral immunity." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 5, pp. 3373-83, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à RAP1A

RAP1A, member of RAS oncogene family (RAP1A), RAS-related protein 1a (Rap1a), RAP1A, member of RAS oncogene family (Rap1a), RAP1A, member of RAS oncogene family a (rap1aa), RAP1A, member of RAS oncogene family L homeolog (rap1a.L), AI848598, G-22K, KREV-1, Krev-1, krev-1, KREV1, krev1, RAP-1A, RAP1, Rap1, rap1, rap 1A, SMGP21, wu:fc66g06, zgc:86676

Protein level used designations for RAP1A

  • C21KG
  • G-22K
  • GTP-binding protein smg p21A
  • RAS-related protein RAP1A
  • Ras-related protein Krev-1
  • ras-related protein Rap-1A
  • RAP1A, member of RAS oncogene family
  • GTP-binding protein SMG-P21A
  • ras-related protein Krev-1
  • RAS-related protein 1a
  • Rap1b
  • GTP-binding protein smg-p21A
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