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RAPTOR Produits

(RAPTOR)

Catégories

This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].

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Catégories RAPTOR en vedette

RAPTOR Anticorps

High quality antibodies with extensive validation data.

RAPTOR recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, DB, IHC (p)
Validations
  • (1)
  • (3)
N° du produit ABIN389879
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN3032434
Quantité 0.4 mL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
N° du produit ABIN700780
Quantité 100 μL
Fiche technique Fiche technique

Dernières publications sur nos produits RAPTOR

Cully, Genevet, Warne, Treins, Liu, Bastien, Baum, Tapon, Leevers, Downward: "A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1." dans: Molecular and cellular biology, Vol. 30, Issue 2, pp. 481-95, (2009) (PubMed).

Wang, Bai, Qin, Zhang, Yi, Teesdale, Zhao, Pober, Tellides: "Interferon-gamma induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase dependent mammalian target of rapamycin raptor complex 1 activation." dans: Circulation research, Vol. 101, Issue 6, pp. 560-9, (2007) (PubMed).

Chu, Rajamanonmani, Li, Bhuvanakantham, Lescar, Ng: "Inhibition of West Nile virus entry by using a recombinant domain III from the envelope glycoprotein." dans: The Journal of general virology, Vol. 86, Issue Pt 2, pp. 405-12, (2005) (PubMed).

Kim, Sarbassov, Ali, King, Latek, Erdjument-Bromage, Tempst, Sabatini: "mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery." dans: Cell, Vol. 110, Issue 2, pp. 163-75, (2002) (PubMed).

Hara, Maruki, Long, Yoshino, Oshiro, Hidayat, Tokunaga, Avruch, Yonezawa: "Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action." dans: Cell, Vol. 110, Issue 2, pp. 177-89, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à RAPTOR

regulatory associated protein of MTOR complex 1 (RPTOR), regulatory associated protein of MTOR, complex 1 (Rptor), 4932417H02Rik, KOG1, Mip1, mKIAA1303, Rap, Raptor, RGD1311784

Protein level used designations for RAPTOR

  • p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats
  • raptor
  • regulatory-associated protein of mTOR
  • p150 target of rapamycin (TOR)-scaffold protein
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