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RASA2 Produits

(RAS P21 Protein Activator 2 (RASA2))

Catégories

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member has a perinuclear localization and is an inositol 1,3,4,5-tetrakisphosphate-binding protein\; a compound suggested to function as a second messenger. [provided by RefSeq, Jul 2008].

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Catégories RASA2 en vedette

RASA2 Anticorps

High quality antibodies with extensive validation data.

RASA2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (2)
N° du produit ABIN7239419
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IF
Validations
  • (1)
N° du produit ABIN7167148
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
  • (1)
N° du produit ABIN6258886
Quantité 100 μL
Fiche technique Fiche technique

Dernières publications sur nos produits RASA2

Arafeh, Qutob, Emmanuel, Keren-Paz, Madore, Elkahloun, Wilmott, Gartner, Di Pizio, Winograd-Katz, Sindiri, Rotkopf, Dutton-Regester, Johansson, Pritchard, Waddell, Hill, Lin, Hevroni, Rosenberg, Khan et al.: "Recurrent inactivating RASA2 mutations in melanoma. ..." dans: Nature genetics, Vol. 47, Issue 12, pp. 1408-10, (2015) (PubMed).

Maekawa, Li, Iwamatsu, Morishita, Yokota, Imai, Kohsaka, Nakamura, Hattori: "A novel mammalian Ras GTPase-activating protein which has phospholipid-binding and Btk homology regions." dans: Molecular and cellular biology, Vol. 14, Issue 10, pp. 6879-85, (1994) (PubMed).

Synonymes et noms alternatifs relatifs à RASA2

RAS p21 protein activator 2 (RASA2), RAS p21 protein activator 2 (Rasa2), 5430433H21Rik, AA517451, AU023900, GAP1M, GAP1m

Protein level used designations for RASA2

  • GTPase-activating protein 1m
  • GTPase-activating protein of RAS
  • ras GTPase-activating protein 2
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