RASGRP4 Produits
(RAS Guanyl Releasing Protein 4 (RASGRP4))
Catégories
The protein encoded by this gene is a member of the Ras guanyl nucleotide-releasing protein (RasGRP) family of Ras guanine nucleotide exchange factors. It contains a Ras exchange motif, a diacylglycerol-binding domain, and two calcium-binding EF hands. This protein was shown to activate H-Ras in a cation-dependent manner in vitro. Expression of this protein in myeloid cell lines was found to be correlated with elevated level of activated RAS protein, and the RAS activation can be greatly enhanced by phorbol ester treatment, which suggested a role of this protein in diacylglycerol regulated cell signaling pathways. Studies of a mast cell leukemia cell line expressing substantial amounts of abnormal transcripts of this gene indicated that this gene may play an important role in the final stages of mast cell development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009].
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Catégories RASGRP4 en vedette
RASGRP4 Anticorps
High quality antibodies with extensive validation data.
RASGRP4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
RASGRP4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (3)
N° du produit
ABIN566740
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p), IF, ICC
Validations
- (3)
N° du produit
ABIN2855910
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, PLA
Validations
- (2)
N° du produit
ABIN530350
Quantité
100 μg
Fiche technique
Fiche technique
RASGRP4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1317507
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1317506
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3081014
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits RASGRP4
: "Galectin-3 regulates RasGRP4-mediated activation of N-Ras and H-Ras." dans: Biochimica et biophysica acta, Vol. 1783, Issue 6, pp. 985-93, (2008) (PubMed).: "RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia." dans: The Journal of biological chemistry, Vol. 277, Issue 34, pp. 30508-14, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à RASGRP4
RAS guanyl releasing protein 4 (RASGRP4), RAS guanyl releasing protein 4 (rasgrp4), RAS guanyl releasing protein 4 (Rasgrp4), RASGRP4Protein level used designations for RASGRP4
- RAS guanyl releasing protein 4
- RAS guanyl-releasing protein 4-like
- RAS guanyl-releasing protein 4
- guanyl nucleotide releasing protein 4
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