RASSF1 Produits
(Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
Catégories
This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011].
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Catégories RASSF1 en vedette
RASSF1 Anticorps
High quality antibodies with extensive validation data.
RASSF1 Kits ELISA
Reliable ELISA kits for a wide range of species.
RASSF1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
RASSF1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (2)
- (4)
N° du produit
ABIN673764
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN6264654
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (3)
N° du produit
ABIN3021712
Quantité
100 μL
Fiche technique
Fiche technique
RASSF1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6959049
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1154468
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5658354
Quantité
96 tests
Fiche technique
Fiche technique
RASSF1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN1098704
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1317520
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1317522
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits RASSF1
: "An association between overexpression of DNA methyltransferase 3B4 and clear cell renal cell carcinoma." dans: Oncotarget, Vol. 8, Issue 12, pp. 19712-19722, (2017) (PubMed).: "Comparison of Selected Protein Levels in Tumour and Surgical Margin in a Group of Patients with Oral Cavity Cancer." dans: Biochemical genetics, Vol. 55, Issue 4, pp. 322-334, (2017) (PubMed).
: "CpG island promoter hypermethylation of Ras association domain family 1A gene contributes to gastric carcinogenesis." dans: Molecular medicine reports, Vol. 11, Issue 4, pp. 3039-46, (2015) (PubMed).
: "Decreased expression of RASSF1A tumor suppressor gene is associated with worse prognosis in clear cell renal cell carcinoma." dans: International journal of oncology, Vol. 48, Issue 1, pp. 55-66, (2015) (PubMed).
: "The RASSF1A tumor suppressor regulates XPA-mediated DNA repair." dans: Molecular and cellular biology, Vol. 35, Issue 1, pp. 277-87, (2014) (PubMed).
: "CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine." dans: Biochemical and biophysical research communications, Vol. 402, Issue 3, pp. 507-14, (2010) (PubMed).
: "Hypermethylation of RASSF1A in human and rhesus placentas." dans: The American journal of pathology, Vol. 170, Issue 3, pp. 941-50, (2007) (PubMed).
: "Mapping geographic zones of cancer risk with epigenetic biomarkers in normal breast tissue." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 12, Issue 22, pp. 6626-36, (2006) (PubMed).
: "The tumor suppressor RASSF1A in human carcinogenesis: an update." dans: Histology and histopathology, Vol. 20, Issue 2, pp. 645-63, (2005) (PubMed).
: "Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter." dans: Molecular and cellular biology, Vol. 25, Issue 10, pp. 3923-33, (2005) (PubMed).
Synonymes et noms alternatifs relatifs à RASSF1
NPR2-like, GATOR1 complex subunit (NPRL2), Ras association (RalGDS/AF-6) domain family 1 (rassf1), Ras association domain family member 1 (RASSF1), putative rassf1 (Smp_157340), Ras association domain family member 1 L homeolog (rassf1.L), Ras association (RalGDS/AF-6) domain family member 1 (Rassf1), Ras association domain family member 1 (Rassf1), 123F2, AA536941, AU044980, NORE2A, RASSF1, RASSF1A, Rassf1A, Rassf1B, Rassf1C, RDA32, REH3P21, wu:fc17f02, zgc:92505, zgc:112224Protein level used designations for RASSF1
- Ras association (RalGDS/AF-6) domain family 1
- Ras association (RalGDS/AF-6) domain family member 1
- ras association domain-containing protein 1
- Ras association domain family 1
- rassf1
- WUGSC:H_LUCA12.5
- cardiac-specific ras association domain family 1 protein
- pancreas-specific ras association domain family 1 protein
- tumor suppressor protein RDA32
- 123F protein
- RASSF1A tumor suppressor
- protein 123F2
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