RBM25 Produits
(RNA Binding Motif Protein 25 (RBM25))
Catégories
RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA (By similarity).
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Catégories RBM25 en vedette
RBM25 Anticorps
High quality antibodies with extensive validation data.
RBM25 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (2)
N° du produit
ABIN7270082
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
IF
Validations
- (1)
N° du produit
ABIN7258448
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Chicken, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
N° du produit
ABIN6748334
Quantité
100 μL
Fiche technique
Fiche technique
RBM25 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6207321
Quantité
96 tests
Fiche technique
Fiche technique
Dernières publications sur nos produits RBM25
: "Detecting endogenous SUMO targets in mammalian cells and tissues." dans: Nature structural & molecular biology, Vol. 20, Issue 4, pp. 525-31, (2013) (PubMed).: "Nuclear cathepsin F regulates activation markers in rat hepatic stellate cells." dans: Molecular biology of the cell, Vol. 19, Issue 10, pp. 4238-48, (2008) (PubMed).
: "Novel splicing factor RBM25 modulates Bcl-x pre-mRNA 5' splice site selection." dans: Molecular and cellular biology, Vol. 28, Issue 19, pp. 5924-36, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à RBM25
RNA binding motif protein 25b (rbm25b), RNA binding motif protein 25 (Rbm25), RNA binding motif protein 25 S homeolog (rbm25.S), RNA binding motif protein 25 (rbm25), RNA binding motif protein 25 (RBM25), putative rna binding motif protein 25 (Smp_078610), 2600011C06Rik, 2610015J01Rik, A130095G20Rik, AI159652, AL023075, AU043498, fi03e10, fSAP94, NET52, RED120, rnpc7, RNPC7, s164, S164, si:ch211-105d18.5, Snu71, wu:fi03e10, zgc:56208Protein level used designations for RBM25
- RNA-binding protein 25
- RNA binding motif protein 25
- RNA-binding protein 25-like
- Arg/Glu/Asp-rich protein, 120 kDa
- RNA-binding motif protein 25
- RNA-binding region (RNP1, RRM) containing 7
- RNA-binding region-containing protein 7
- U1 small nuclear ribonucleoprotein 1SNRP homolog
- arg/Glu/Asp-rich protein of 120 kDa
- functional spliceosome-associated protein 94
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