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RC3H1 Produits

(Ring Finger and CCCH-Type Domains 1 (RC3H1))
RC3H1, or roquin, encodes a highly conserved member of the RING type ubiquitin ligase protein family (Vinuesa et al., 2005 [PubMed 15917799]). The roquin protein is distinguished by the presence of a CCCH zinc finger found in RNA-binding proteins, and localization to cytosolic RNA granules implicated in regulating mRNA translation and stability.[supplied by OMIM, Mar 2008].

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Catégories RC3H1 en vedette

RC3H1 Anticorps

High quality antibodies with extensive validation data.

RC3H1 Kits ELISA

Reliable ELISA kits for a wide range of species.

RC3H1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

RC3H1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
N° du produit ABIN7270049
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF
Validations
N° du produit ABIN6991828
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IP
Validations
N° du produit ABIN7452216
Quantité 100 μg
Fiche technique Fiche technique

RC3H1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1156308
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1156309
Quantité 96 tests
Fiche technique Fiche technique

RC3H1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3094903
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3135151
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2730649
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits RC3H1

Srivastava, Duan, Kershaw, Athanasopoulos, Yeo, Ose, Hu, Brown, Jergic, Patel, Pratama, Richards, Verma, Jones, Heissmeyer, Preiss, Dixon, Chong, Babon, Vinuesa: "Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis." dans: Nature communications, Vol. 6, pp. 6253, (2015) (PubMed).

Murakawa, Hinz, Mothes, Schuetz, Uhl, Wyler, Yasuda, Mastrobuoni, Friedel, Dölken, Kempa, Schmidt-Supprian, Blüthgen, Backofen, Heinemann, Wolf, Scheidereit, Landthaler: "RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway." dans: Nature communications, Vol. 6, pp. 7367, (2015) (PubMed).

Ramiscal, Parish, Lee-Young, Babon, Blagih, Pratama, Martin, Hawley, Cappello, Nieto, Ellyard, Kershaw, Sweet, Goodnow, Jones, Febbraio, Vinuesa, Athanasopoulos: "Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation." dans: eLife, Vol. 4, (2015) (PubMed).

Auguste, Travert, Tarte, Amé-Thomas, Artchounin, Martin-Garcia, de Reynies, de Leval, Gaulard, Delfau-Larue: "ROQUIN/RC3H1 alterations are not found in angioimmunoblastic T-cell lymphoma." dans: PLoS ONE, Vol. 8, Issue 6, pp. e64536, (2013) (PubMed).

Kim, Ji, Kim, Yu, Shin, Yuh, Bae, Park, Yi, Kim, Park, Yoon, Lee, Lee, Ryoo: "The role of Roquin overexpression in the modulation of signaling during in vitro and ex vivo T-cell activation." dans: Biochemical and biophysical research communications, Vol. 417, Issue 1, pp. 280-6, (2012) (PubMed).

Bertossi, Aichinger, Sansonetti, Lech, Neff, Pal, Wunderlich, Anders, Klein, Schmidt-Supprian: "Loss of Roquin induces early death and immune deregulation but not autoimmunity." dans: The Journal of experimental medicine, Vol. 208, Issue 9, pp. 1749-56, (2011) (PubMed).

Yan, Cao, Reilly, Young, Garcia, Mishra: "Histone deacetylase 9 deficiency protects against effector T cell-mediated systemic autoimmunity." dans: The Journal of biological chemistry, Vol. 286, Issue 33, pp. 28833-43, (2011) (PubMed).

Athanasopoulos, Barker, Yu, Tan, Srivastava, Contreras, Wang, Lam, Brown, Goodnow, Dixon, Leedman, Saint, Vinuesa: "The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs." dans: The FEBS journal, Vol. 277, Issue 9, pp. 2109-27, (2010) (PubMed).

Synonymes et noms alternatifs relatifs à RC3H1

ring finger and CCCH-type domains 1 (RC3H1), ring finger and CCCH-type domains 1a (rc3h1a), ring finger and CCCH-type zinc finger domains 1 (RC3H1), RING CCCH (C3H) domains 1 (Rc3h1), ring finger and CCCH-type domains 1 (Rc3h1), ring finger and CCCH-type domains 1 L homeolog (rc3h1.L), 5730557L09Rik, Gm551, mKIAA2025, N28103, RC3H1, rc3h1, RGD1563512, RNF198, ROQUIN, si:dkey-192m14.4

Protein level used designations for RC3H1

  • RING finger and C3H zinc finger protein 1
  • RING finger protein 198
  • probable E3 ubiquitin-protein ligase Roquin
  • ring finger and CCCH-type zinc finger domains 1
  • roquin
  • roquin-like
  • ring finger and CCCH-type domains 1
  • protein Sanroque
  • RING CCCH (C3H) domains 1
  • RING finger and CCCH-type zinc finger domain-containing protein 1
  • roquin-1
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