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RENT2/UPF2 Produits

(UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Catégories

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene\\\\; both variants encode the same protein. [provided by RefSeq, Jul 2008].

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Catégories RENT2/UPF2 en vedette

RENT2/UPF2 Anticorps

High quality antibodies with extensive validation data.

RENT2/UPF2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB
Validations
  • (3)
N° du produit ABIN6149941
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS
Validations
  • (2)
N° du produit ABIN654649
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (3)
N° du produit ABIN6570914
Quantité 200 μL
Fiche technique Fiche technique

RENT2/UPF2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3095007
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2735035
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits RENT2/UPF2

Cheruiyot, Li, Nickless, Roth, Fitzpatrick, You: "Compound C inhibits nonsense-mediated RNA decay independently of AMPK." dans: PLoS ONE, Vol. 13, Issue 10, pp. e0204978, (2019) (PubMed).

Nickless, Jackson, Marasa, Nugent, Mercer, Piwnica-Worms, You: "Intracellular calcium regulates nonsense-mediated mRNA decay." dans: Nature medicine, Vol. 20, Issue 8, pp. 961-6, (2014) (PubMed).

Hosoda, Kim, Lejeune, Maquat: "CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells." dans: Nature structural & molecular biology, Vol. 12, Issue 10, pp. 893-901, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à RENT2/UPF2

UPF2, regulator of nonsense mediated mRNA decay (UPF2), UPF2 regulator of nonsense transcripts homolog (yeast) (Upf2), UPF2, regulator of nonsense mediated mRNA decay (Upf2), UPF2 regulator of nonsense transcripts homolog (yeast) (UPF2), UPF2 regulator of nonsense transcripts homolog (yeast) (upf2), HUPF2, RENT2, smg-3

Protein level used designations for RENT2/UPF2

  • nonsense mRNA reducing factor 2
  • regulator of nonsense transcripts 2
  • smg-3 homolog, nonsense mediated mRNA decay factor
  • up-frameshift suppressor 2 homolog
  • yeast Upf2p homolog
  • UPF2 regulator of nonsense transcripts homolog (yeast)
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