Retinal Pigment Epithelium-Specific Protein 65kDa Produits
(Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))
Catégories
This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa. [provided by RefSeq, Jul 2008].
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Catégories Retinal Pigment Epithelium-Specific Protein 65kDa en vedette
Retinal Pigment Epithelium-Specific Protein 65kDa Anticorps
High quality antibodies with extensive validation data.
Retinal Pigment Epithelium-Specific Protein 65kDa Kits ELISA
Reliable ELISA kits for a wide range of species.
Retinal Pigment Epithelium-Specific Protein 65kDa Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Retinal Pigment Epithelium-Specific Protein 65kDa recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF, IHC
Validations
- (5)
N° du produit
ABIN7269933
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
N° du produit
ABIN7167824
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (3)
N° du produit
ABIN6147090
Quantité
100 μL
Fiche technique
Fiche technique
Retinal Pigment Epithelium-Specific Protein 65kDa recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6221142
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6221145
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5593944
Quantité
96 tests
Fiche technique
Fiche technique
Retinal Pigment Epithelium-Specific Protein 65kDa recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7422823
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7422820
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2731119
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Retinal Pigment Epithelium-Specific Protein 65kDa
: "Advantages of nanofibrous membranes for culturing of primary RPE cells compared to commercial scaffolds." dans: Acta ophthalmologica, (2021) (PubMed).: "The role of Wnt/β-catenin signaling in the restoration of induced pluripotent stem cell-derived retinal pigment epithelium after laser photocoagulation." dans: Lasers in medical science, Vol. 34, Issue 3, pp. 571-581, (2019) (PubMed).
: "High-throughput screening identifies compounds that protect RPE cells from physiological stressors present in AMD." dans: Experimental eye research, Vol. 185, pp. 107641, (2019) (PubMed).
: "Conversion of all-trans-retinal into all-trans-retinal dimer reflects an alternative metabolic/antidotal pathway of all-trans-retinal in the retina." dans: The Journal of biological chemistry, Vol. 293, Issue 37, pp. 14507-14519, (2019) (PubMed).
: "Optimizing Donor Cellular Dissociation and Subretinal Injection Parameters for Stem Cell-Based Treatments." dans: Stem cells translational medicine, Vol. 8, Issue 8, pp. 797-809, (2019) (PubMed).
: "Flow Cytometric Detection of Circulating Osteosarcoma Cells in Dogs." dans: Cytometry. Part A : the journal of the International Society for Analytical Cytology, (2019) (PubMed).
: "Cooperation of Rel family members in regulating Aβ1-40-mediated pro-inflammatory cytokine secretion by retinal pigment epithelial cells." dans: Cell death & disease, Vol. 8, Issue 10, pp. e3115, (2018) (PubMed).
: "An Acute Injury Model for the Phenotypic Characteristics of Geographic Atrophy." dans: Investigative ophthalmology & visual science, Vol. 59, Issue 4, pp. AMD143-AMD151, (2018) (PubMed).
: "Organoid technology for retinal repair." dans: Developmental biology, Vol. 433, Issue 2, pp. 132-143, (2018) (PubMed).
: "Aberrant early endosome biogenesis mediates complement activation in the retinal pigment epithelium in models of macular degeneration." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 36, pp. 9014-9019, (2018) (PubMed).
Synonymes et noms alternatifs relatifs à Retinal Pigment Epithelium-Specific Protein 65kDa
RPE65, retinoid isomerohydrolase (RPE65), retinal pigment epithelium 65 (Rpe65), neither inactivation nor afterpotential B (ninaB), RPE65, retinoid isomerohydrolase (Rpe65), retinal pigment epithelium-specific protein 65kDa S homeolog (rpe65.S), retinal pigment epithelium-specific protein 65kDa L homeolog (rpe65.L), RPE65 homolog (rpe65), retinal pigment epithelium-specific protein 65kDa (rpe65), retinal pigment epithelium-specific protein 65c (rpe65c), retinal pigment epithelium-specific protein 65b (rpe65b), retinal pigment epithelium-specific protein 65a (rpe65a), 13cIMH, 65kDa, A930029L06Rik, anon-WO0148162.1, anon-WO0148163.1, beta-diox, CG9347, DmelCG9347, DRPE65, LCA2, MGC52887, MGC85437, MGC154296, Mord1, mRPE65, rd12, RP20, RPE56a, RPE56b, RPE56c, RPE65, rpe65, rpepa, rpepb, si:ch211-198n5.5, si:ch211-198n5.12, sRPE65, wu:fc74c09, zgc:73213, zgc:110538Protein level used designations for Retinal Pigment Epithelium-Specific Protein 65kDa
- RBP-binding membrane protein
- all-trans-retinyl-palmitate hydrolase
- p63
- retinal pigment epithelium-specific 65 kDa protein
- retinitis pigmentosa 20 (autosomal recessive)
- retinoid isomerohydrolase
- retinol isomerase
- modifier of retinal degeneration 1
- retinal pigment epithelium, 65 kDa
- neither inactivation nor afterpotential B
- CG9347-PA
- ninaB-PA
- beta-carotene dioxygenase
- retinal pigment epithelium 65-like
- retinal pigment epithelium-specific protein (65kD)
- retinal pigment epithelium-specific protein 65kDa
- retinal pigment epithelium abundant protein RPE65
- rpe65 gene for retinal pigment epithelium-specific protein
- RPE65 homolog
- retinoid isomerohydrolase-like
- All-trans-retinyl ester 13-cis isomerohydrolase C
- All-trans-retinylester 11-cis isomerohydrolase C
- Retinal pigment epithelium-specific 65 kDa protein homolog C
- retinal Mueller cells isomerohydrolase
- 13cIMH
- Retinal pigment epithelium-specific 65 kDa protein homolog B
- all-trans-retinyl ester 13-cis isomerohydrolase
- retinal pigment epithelium 65b
- retinal pigment epithelium-specific 65 kDa protein homolog B
- retinal pigment epithelium-specific protein b
- All-trans-retinylester 11-cis isomerohydrolase A
- Retinal pigment epithelium-specific 65 kDa protein homolog A
- all-trans-retinylester 11-cis isomerohydrolase A
- retinal pigment epithelium 65a
- retinal pigment epithelium-specific 65 kDa protein homolog A
- retinal pigment epithelium-specific protein a
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