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Retinal Pigment Epithelium-Specific Protein 65kDa Produits

(Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))
This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa. [provided by RefSeq, Jul 2008].

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Catégories Retinal Pigment Epithelium-Specific Protein 65kDa en vedette

Retinal Pigment Epithelium-Specific Protein 65kDa Anticorps

High quality antibodies with extensive validation data.

Retinal Pigment Epithelium-Specific Protein 65kDa Kits ELISA

Reliable ELISA kits for a wide range of species.

Retinal Pigment Epithelium-Specific Protein 65kDa Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Retinal Pigment Epithelium-Specific Protein 65kDa recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF, IHC
Validations
  • (5)
N° du produit ABIN7269933
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
N° du produit ABIN7167824
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (3)
N° du produit ABIN6147090
Quantité 100 μL
Fiche technique Fiche technique

Retinal Pigment Epithelium-Specific Protein 65kDa recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6221142
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6221145
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5593944
Quantité 96 tests
Fiche technique Fiche technique

Retinal Pigment Epithelium-Specific Protein 65kDa recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7422823
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7422820
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2731119
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Retinal Pigment Epithelium-Specific Protein 65kDa

Tichotová, Studenovska, Petrovski, Popelka, Nemesh, Sedláčková, Drutovič, Rohiwal, Jendelová, Erceg, Brymová, Artero-Castro, Lytvynchuk, Straňák, Ellederová, Motlík, Ardan: "Advantages of nanofibrous membranes for culturing of primary RPE cells compared to commercial scaffolds." dans: Acta ophthalmologica, (2021) (PubMed).

Cho, Park, Lee, Nah, Park, Yang, Madrakhimov, Lyu, Park: "The role of Wnt/β-catenin signaling in the restoration of induced pluripotent stem cell-derived retinal pigment epithelium after laser photocoagulation." dans: Lasers in medical science, Vol. 34, Issue 3, pp. 571-581, (2019) (PubMed).

Cai, Gong, Abriola, Hoyer, Nyscf Global Stem Cell Array Team, Noggle, Paull, Del Priore, Fields: "High-throughput screening identifies compounds that protect RPE cells from physiological stressors present in AMD." dans: Experimental eye research, Vol. 185, pp. 107641, (2019) (PubMed).

Gao, Liao, Chen, Liao, He, Chen, Ma, Liu, Wu: "Conversion of all-trans-retinal into all-trans-retinal dimer reflects an alternative metabolic/antidotal pathway of all-trans-retinal in the retina." dans: The Journal of biological chemistry, Vol. 293, Issue 37, pp. 14507-14519, (2019) (PubMed).

Scruggs, Jiao, Cranston, Kaalberg, Wang, Russell, Wiley, Mullins, Stone, Tucker, Sohn: "Optimizing Donor Cellular Dissociation and Subretinal Injection Parameters for Stem Cell-Based Treatments." dans: Stem cells translational medicine, Vol. 8, Issue 8, pp. 797-809, (2019) (PubMed).

Wright, Brisson, Wood, Oblak, Mutsaers, Sabine, Skowronski, Belanger, Tiessen, Bienzle: "Flow Cytometric Detection of Circulating Osteosarcoma Cells in Dogs." dans: Cytometry. Part A : the journal of the International Society for Analytical Cytology, (2019) (PubMed).

Sun, Huang, Liang, Li, Shen, She, Feng, Luo, Liu, Sun: "Cooperation of Rel family members in regulating Aβ1-40-mediated pro-inflammatory cytokine secretion by retinal pigment epithelial cells." dans: Cell death & disease, Vol. 8, Issue 10, pp. e3115, (2018) (PubMed).

Bhutto, Ogura, Baldeosingh, McLeod, Lutty, Edwards: "An Acute Injury Model for the Phenotypic Characteristics of Geographic Atrophy." dans: Investigative ophthalmology & visual science, Vol. 59, Issue 4, pp. AMD143-AMD151, (2018) (PubMed).

Llonch, Carido, Ader: "Organoid technology for retinal repair." dans: Developmental biology, Vol. 433, Issue 2, pp. 132-143, (2018) (PubMed).

Kaur, Tan, Rathnasamy, La Cunza, Germer, Toops, Fernandes, Blenkinsop, Lakkaraju: "Aberrant early endosome biogenesis mediates complement activation in the retinal pigment epithelium in models of macular degeneration." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 36, pp. 9014-9019, (2018) (PubMed).

Synonymes et noms alternatifs relatifs à Retinal Pigment Epithelium-Specific Protein 65kDa

RPE65, retinoid isomerohydrolase (RPE65), retinal pigment epithelium 65 (Rpe65), neither inactivation nor afterpotential B (ninaB), RPE65, retinoid isomerohydrolase (Rpe65), retinal pigment epithelium-specific protein 65kDa S homeolog (rpe65.S), retinal pigment epithelium-specific protein 65kDa L homeolog (rpe65.L), RPE65 homolog (rpe65), retinal pigment epithelium-specific protein 65kDa (rpe65), retinal pigment epithelium-specific protein 65c (rpe65c), retinal pigment epithelium-specific protein 65b (rpe65b), retinal pigment epithelium-specific protein 65a (rpe65a), 13cIMH, 65kDa, A930029L06Rik, anon-WO0148162.1, anon-WO0148163.1, beta-diox, CG9347, DmelCG9347, DRPE65, LCA2, MGC52887, MGC85437, MGC154296, Mord1, mRPE65, rd12, RP20, RPE56a, RPE56b, RPE56c, RPE65, rpe65, rpepa, rpepb, si:ch211-198n5.5, si:ch211-198n5.12, sRPE65, wu:fc74c09, zgc:73213, zgc:110538

Protein level used designations for Retinal Pigment Epithelium-Specific Protein 65kDa

  • RBP-binding membrane protein
  • all-trans-retinyl-palmitate hydrolase
  • p63
  • retinal pigment epithelium-specific 65 kDa protein
  • retinitis pigmentosa 20 (autosomal recessive)
  • retinoid isomerohydrolase
  • retinol isomerase
  • modifier of retinal degeneration 1
  • retinal pigment epithelium, 65 kDa
  • neither inactivation nor afterpotential B
  • CG9347-PA
  • ninaB-PA
  • beta-carotene dioxygenase
  • retinal pigment epithelium 65-like
  • retinal pigment epithelium-specific protein (65kD)
  • retinal pigment epithelium-specific protein 65kDa
  • retinal pigment epithelium abundant protein RPE65
  • rpe65 gene for retinal pigment epithelium-specific protein
  • RPE65 homolog
  • retinoid isomerohydrolase-like
  • All-trans-retinyl ester 13-cis isomerohydrolase C
  • All-trans-retinylester 11-cis isomerohydrolase C
  • Retinal pigment epithelium-specific 65 kDa protein homolog C
  • retinal Mueller cells isomerohydrolase
  • 13cIMH
  • Retinal pigment epithelium-specific 65 kDa protein homolog B
  • all-trans-retinyl ester 13-cis isomerohydrolase
  • retinal pigment epithelium 65b
  • retinal pigment epithelium-specific 65 kDa protein homolog B
  • retinal pigment epithelium-specific protein b
  • All-trans-retinylester 11-cis isomerohydrolase A
  • Retinal pigment epithelium-specific 65 kDa protein homolog A
  • all-trans-retinylester 11-cis isomerohydrolase A
  • retinal pigment epithelium 65a
  • retinal pigment epithelium-specific 65 kDa protein homolog A
  • retinal pigment epithelium-specific protein a
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