Retinoblastoma Binding Protein 8 Produits
(Retinoblastoma Binding Protein 8 (RBBP8))
Catégories
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008].
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Catégories Retinoblastoma Binding Protein 8 en vedette
Retinoblastoma Binding Protein 8 Anticorps
High quality antibodies with extensive validation data.
Retinoblastoma Binding Protein 8 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Retinoblastoma Binding Protein 8 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (3)
N° du produit
ABIN604928
Quantité
50 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
N° du produit
ABIN7150164
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (1)
- (1)
N° du produit
ABIN2856639
Quantité
100 μL
Fiche technique
Fiche technique
Retinoblastoma Binding Protein 8 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6203591
Quantité
96 tests
Fiche technique
Fiche technique
Retinoblastoma Binding Protein 8 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1317559
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3091883
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3136083
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits Retinoblastoma Binding Protein 8
: "ZNF830 mediates cancer chemoresistance through promoting homologous-recombination repair." dans: Nucleic acids research, Vol. 46, Issue 3, pp. 1266-1279, (2018) (PubMed).: "ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks." dans: Molecular cell, Vol. 68, Issue 1, pp. 61-75.e5, (2017) (PubMed).
: "Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination." dans: Nucleic acids research, Vol. 44, Issue 12, pp. 5702-16, (2016) (PubMed).
: "Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1." dans: Oncotarget, Vol. 7, Issue 36, pp. 57679-57693, (2016) (PubMed).
: "RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner." dans: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 6, pp. 787-98, (2016) (PubMed).
: "MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex." dans: Nature communications, Vol. 6, pp. 7744, (2015) (PubMed).
: "FANCD2 binds CtIP and regulates DNA-end resection during DNA interstrand crosslink repair." dans: Cell reports, Vol. 7, Issue 4, pp. 1039-47, (2014) (PubMed).
: "Quantitation of DNA double-strand break resection intermediates in human cells." dans: Nucleic acids research, Vol. 42, Issue 3, pp. e19, (2014) (PubMed).
: "Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection." dans: Molecular cell, Vol. 54, Issue 6, pp. 1022-33, (2014) (PubMed).
: "SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage." dans: Genes & development, Vol. 26, Issue 11, pp. 1196-208, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à Retinoblastoma Binding Protein 8
RB binding protein 8, endonuclease (RBBP8), retinoblastoma binding protein 8, endonuclease (Rbbp8), RB binding protein 8, endonuclease (Rbbp8), retinoblastoma binding protein 8 L homeolog (rbbp8.L), retinoblastoma binding protein 8 (rbbp8), 9930104E21Rik, COM1, CTIP, CtIP, DKFZp469K0714, JWDS, RBBP-8, RBBP8, RGD1308872, RIM, SAE2, SCKL2Protein level used designations for Retinoblastoma Binding Protein 8
- CTBP-interacting protein
- DNA endonuclease RBBP8
- RBBP-8
- sporulation in the absence of SPO11 protein 2 homolog
- ctBP-interacting protein
- retinoblastoma-binding protein 8
- retinoblastoma binding protein 8
- CtBP-interacting protein
- retinoblastoma-binding protein 8-like
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