RFX5 Produits
(Regulatory Factor X 5 (RFX5))
Catégories
A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS\; MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined. [provided by RefSeq, Jul 2008].
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Catégories RFX5 en vedette
RFX5 Anticorps
High quality antibodies with extensive validation data.
RFX5 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
RFX5 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, GS
Validations
- (3)
- (2)
N° du produit
ABIN106544
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (3)
N° du produit
ABIN948403
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
N° du produit
ABIN7150384
Quantité
100 μL
Fiche technique
Fiche technique
RFX5 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6207337
Quantité
96 tests
Fiche technique
Fiche technique
RFX5 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1317888
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1317890
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2730796
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits RFX5
: "Increased error-free DNA repair gene expression through reprogramming in human iPS cells." dans: Regenerative therapy, Vol. 11, pp. 101-105, (2019) (PubMed).: "The transcription factor RFX5 is a transcriptional activator of the TPP1 gene in hepatocellular carcinoma." dans: Oncology reports, Vol. 37, Issue 1, pp. 289-296, (2017) (PubMed).
: "Degradation, Promoter Recruitment and Transactivation Mediated by the Extreme N-Terminus of MHC Class II Transactivator CIITA Isoform III." dans: PLoS ONE, Vol. 11, Issue 2, pp. e0148753, (2016) (PubMed).
: "In contrast to Chlamydia trachomatis, Waddlia chondrophila grows in human cells without inhibiting apoptosis, fragmenting the Golgi apparatus, or diverting post-Golgi sphingomyelin transport." dans: Infection and immunity, Vol. 83, Issue 8, pp. 3268-80, (2015) (PubMed).
: "PML promotes MHC class II gene expression by stabilizing the class II transactivator." dans: The Journal of cell biology, Vol. 199, Issue 1, pp. 49-63, (2012) (PubMed).
: "HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells." dans: Journal of molecular and cellular cardiology, Vol. 46, Issue 3, pp. 292-9, (2009) (PubMed).
: "Identifying catalytic residues in CPAF, a Chlamydia-secreted protease." dans: Archives of biochemistry and biophysics, Vol. 485, Issue 1, pp. 16-23, (2009) (PubMed).
: "Regulatory factor for X-box family proteins differentially interact with histone deacetylases to repress collagen alpha2(I) gene (COL1A2) expression." dans: The Journal of biological chemistry, Vol. 281, Issue 14, pp. 9260-70, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à RFX5
regulatory factor X5 (RFX5), regulatory factor X, 5 (influences HLA class II expression) (Rfx5), regulatory factor X5 (Rfx5)Protein level used designations for RFX5
- DNA-binding protein RFX5
- regulatory factor X 5
- DNA-binding protein Rfx5
- regulatory factor X, 5
- regulator factor X 5
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