RGS14 Produits
(Regulator of G-Protein Signaling 14 (RGS14))
Catégories
This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008].
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Catégories RGS14 en vedette
RGS14 Anticorps
High quality antibodies with extensive validation data.
RGS14 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
RGS14 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, IHC (p), IF
Validations
- (3)
N° du produit
ABIN524067
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
N° du produit
ABIN2856368
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (2)
N° du produit
ABIN6258314
Quantité
100 μL
Fiche technique
Fiche technique
RGS14 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6221040
Quantité
96 tests
Fiche technique
Fiche technique
RGS14 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1317939
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1317937
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124814
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits RGS14
: "Mossy fiber sprouting into the hippocampal region CA2 in patients with temporal lobe epilepsy." dans: Hippocampus, Vol. 31, Issue 6, pp. 580-592, (2021) (PubMed).: "Novel connection between newborn granule neurons and the hippocampal CA2 field." dans: Experimental neurology, Vol. 263, pp. 285-92, (2014) (PubMed).
: "Postnatal developmental expression of regulator of G protein signaling 14 (RGS14) in the mouse brain." dans: The Journal of comparative neurology, Vol. 522, Issue 1, pp. 186-203, (2014) (PubMed).
: "Cell type-specific genetic and optogenetic tools reveal hippocampal CA2 circuits." dans: Nature neuroscience, Vol. 17, Issue 2, pp. 269-79, (2014) (PubMed).
: "The hippocampal CA2 region is essential for social memory." dans: Nature, Vol. 508, Issue 7494, pp. 88-92, (2014) (PubMed).
: "Assembly and function of the regulator of G protein signaling 14 (RGS14)·H-Ras signaling complex in live cells are regulated by G?i1 and G?i-linked G protein-coupled receptors." dans: The Journal of biological chemistry, Vol. 288, Issue 5, pp. 3620-31, (2013) (PubMed).
: "Delta-opioid receptors mediate unique plasticity onto parvalbumin-expressing interneurons in area CA2 of the hippocampus." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 36, pp. 14567-78, (2013) (PubMed).
: "Activation of the regulator of G protein signaling 14-G?i1-GDP signaling complex is regulated by resistance to inhibitors of cholinesterase-8A." dans: Biochemistry, Vol. 50, Issue 5, pp. 752-62, (2011) (PubMed).
: "RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 39, pp. 16994-8, (2010) (PubMed).
: "Molecular cloning and expression analysis of rat Rgs12 and Rgs14." dans: Biochemical and biophysical research communications, Vol. 233, Issue 3, pp. 770-7, (1997) (PubMed).
Synonymes et noms alternatifs relatifs à RGS14
regulator of G protein signaling 14 (RGS14), regulator of G-protein signaling 14 (Rgs14), regulator of G-protein signaling 14 L homeolog (rgs14.L), regulator of G-protein signaling 14 (RGS14), regulator of G-protein signalling 14 (rgs14), regulator of G protein signaling 14 (Rgs14), regulator of G protein signaling 14a (rgs14a), MGC80558, RGS14, rgs14, RPIP1, wu:fi04g12Protein level used designations for RGS14
- regulator of G-protein signalling 14
- RAP1/RAP2-interacting protein
- rap1/rap2 interacting protein
- regulator of G-protein signaling 14
- Regulator of G-protein signaling 14
- regulator of G-protein signaling 14-like
- LOW QUALITY PROTEIN: regulator of G-protein signaling 14
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