RHEB Produits
(Ras Homolog Enriched in Brain (RHEB))
Catégories
This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq, Jul 2008].
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Catégories RHEB en vedette
RHEB Anticorps
High quality antibodies with extensive validation data.
RHEB Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
RHEB recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (6)
N° du produit
ABIN519784
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
N° du produit
ABIN7154592
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (2)
N° du produit
ABIN704771
Quantité
100 μL
Fiche technique
Fiche technique
RHEB recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6951226
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6207342
Quantité
96 tests
Fiche technique
Fiche technique
RHEB recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124780
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN666866
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1317998
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits RHEB
: "RHEB: a potential regulator of chondrocyte phenotype for cartilage tissue regeneration." dans: Journal of tissue engineering and regenerative medicine, (2016) (PubMed).: "In vivo AAV1 transduction with hRheb(S16H) protects hippocampal neurons by BDNF production." dans: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 23, Issue 3, pp. 445-55, (2015) (PubMed).
: "Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome." dans: Cell, Vol. 156, Issue 4, pp. 771-85, (2014) (PubMed).
: "Formation of endothelial lumens requires a coordinated PKCepsilon-, Src-, Pak- and Raf-kinase-dependent signaling cascade downstream of Cdc42 activation." dans: Journal of cell science, Vol. 122, Issue Pt 11, pp. 1812-22, (2009) (PubMed).
: "Phospholipase D1 is an effector of Rheb in the mTOR pathway." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 24, pp. 8286-91, (2008) (PubMed).
: "Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38." dans: Science (New York, N.Y.), Vol. 318, Issue 5852, pp. 977-80, (2007) (PubMed).
: "Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling." dans: Genes & development, Vol. 17, Issue 15, pp. 1829-34, (2003) (PubMed).
: "Rheb is an essential regulator of S6K in controlling cell growth in Drosophila." dans: Nature cell biology, Vol. 5, Issue 6, pp. 559-65, (2003) (PubMed).
: "Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins." dans: Nature cell biology, Vol. 5, Issue 6, pp. 578-81, (2003) (PubMed).
: "Rheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals." dans: Molecular and cellular biology, Vol. 17, Issue 2, pp. 921-33, (1997) (PubMed).
Synonymes et noms alternatifs relatifs à RHEB
Ras homolog, mTORC1 binding (RHEB), Ras homolog enriched in brain (Rheb), Ras homolog, mTORC1 binding (Rheb), Ras homolog enriched in brain (RHEB), Ras homolog, mTORC1 binding (rheb), ras homolog enriched in brain (rheb), Ras homolog, mTORC1 binding L homeolog (rheb.L), CG1081, Dmel\CG1081, Dm Rheb, DmRheb, DReb, dRheb, Q9VND8, RHEB, RheB, rheb, RHEB2, rheb2Protein level used designations for RHEB
- GTP-binding protein Rheb
- Ras homolog enriched in brain 2
- RAS-homolog enriched in brain
- Ras homolog enriched in brain
- ras homolog enriched in brain
- GTP-binding protein rheb
- CG1081 gene product from transcript CG1081-RA
- CG1081-PA
- CG1081-PB
- RAS homolog enriched in brain
- Ras homolog enriched in brain ortholog
- Ras homologue enriched in brain
- Ras homology enriched in brain
- Rheb-PA
- Rheb-PB
- Ras homolog enriched in brain L homeolog
- Ras homolog, mTORC1 binding L homeolog
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