RIPK1 Produits
(Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))
Catégories
Serine-threonine kinase which transduces inflammatory and cell-death signals (necroptosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules. Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation. Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death. RIPK1 and RIPK3 association, in particular, forms a necroptosis-inducing complex.
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Catégories RIPK1 en vedette
RIPK1 Anticorps
High quality antibodies with extensive validation data.
RIPK1 Kits ELISA
Reliable ELISA kits for a wide range of species.
RIPK1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
RIPK1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
N° du produit
ABIN7441202
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (7)
N° du produit
ABIN7441205
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, IF
Validations
- (6)
N° du produit
ABIN6146959
Quantité
100 μL
Fiche technique
Fiche technique
RIPK1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6959056
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969845
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969846
Quantité
96 tests
Fiche technique
Fiche technique
RIPK1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (2)
- (1)
N° du produit
ABIN1318108
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124799
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1318110
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits RIPK1
: "Isolation and characterization of cluster of differentiation 9-positive ependymal cells as potential adult neural stem/progenitor cells in the third ventricle of adult rats." dans: Cell and tissue research, Vol. 379, Issue 3, pp. 497-509, (2020) (PubMed).: "Modulation of lung cancer cell plasticity and heterogeneity with the restoration of cisplatin sensitivity by neurotensin antibody." dans: Cancer letters, Vol. 444, pp. 147-161, (2019) (PubMed).
: "Silencing of A20 Aggravates Neuronal Death and Inflammation After Traumatic Brain Injury: A Potential Trigger of Necroptosis." dans: Frontiers in molecular neuroscience, Vol. 12, pp. 222, (2019) (PubMed).
: "Necroptosis in pulmonary macrophages mediates lipopolysaccharide-induced lung inflammatory injury by activating ZBP-1." dans: International immunopharmacology, Vol. 77, pp. 105944, (2019) (PubMed).
: "Transcription modulation by CDK9 regulates inflammatory genes and RIPK3-MLKL-mediated necroptosis in periodontitis progression." dans: Scientific reports, Vol. 9, Issue 1, pp. 17369, (2019) (PubMed).
: "TDP-43 accelerates age-dependent degeneration of interneurons." dans: Scientific reports, Vol. 7, Issue 1, pp. 14972, (2018) (PubMed).
: "Targeting necroptotic cell death pathway by high-intensity interval training (HIIT) decreases development of post-ischemic adverse remodelling after myocardial ischemia / reperfusion injury." dans: Journal of cell communication and signaling, (2018) (PubMed).
: "Vascular peroxide 1 promotes ox-LDL-induced programmed necrosis in endothelial cells through a mechanism involving β-catenin signaling." dans: Atherosclerosis, Vol. 274, pp. 128-138, (2018) (PubMed).
: "Bifidobacterial recombinant thymidine kinase-ganciclovir gene therapy system induces FasL and TNFR2 mediated antitumor apoptosis in solid tumors." dans: BMC cancer, Vol. 16, pp. 545, (2017) (PubMed).
: "Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosis." dans: Cell death & disease, Vol. 7, Issue 6, pp. e2287, (2016) (PubMed).
Synonymes et noms alternatifs relatifs à RIPK1
receptor interacting serine/threonine kinase 1 (RIPK1), receptor (TNFRSF)-interacting serine-threonine kinase 1 (Ripk1), receptor interacting serine/threonine kinase 1 (Ripk1), receptor interacting serine/threonine kinase 1 L homeolog (ripk1.L), D330015H01Rik, Rinp, RIP, RIP1, Rip1, rip1, ripk1, xrip1, xRIP1betaProtein level used designations for RIPK1
- RIP-1
- cell death protein RIP
- receptor interacting protein
- receptor-interacting protein 1
- receptor-interacting serine/threonine-protein kinase 1
- serine/threonine-protein kinase RIP
- receptor (TNFRSF)-interacting serine-threonine kinase 1
- receptor interacting serine/threonine kinase 1 L homeolog
- receptor-interacting protein 1 beta
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