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RNASEL Produits

(Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL))
This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele. [provided by RefSeq, Jul 2008].

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Catégories RNASEL en vedette

RNASEL Anticorps

High quality antibodies with extensive validation data.

RNASEL Kits ELISA

Reliable ELISA kits for a wide range of species.

RNASEL Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

RNASEL recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB
Validations
  • (4)
N° du produit ABIN6146994
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (3)
N° du produit ABIN7264894
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
N° du produit ABIN7435379
Quantité 100 μL
Fiche technique Fiche technique

RNASEL recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959174
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5658504
Quantité 96 tests
Fiche technique Fiche technique

RNASEL recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1318166
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7402817
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7397231
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits RNASEL

Fabre, Salehzada, Lambert, Boo Seok, Zhou, Mercier, Bisbal: "RNase L controls terminal adipocyte differentiation, lipids storage and insulin sensitivity via CHOP10 mRNA regulation." dans: Cell death and differentiation, Vol. 19, Issue 9, pp. 1470-81, (2012) (PubMed).

Al-Haj, Blackshear, Khabar: "Regulation of p21/CIP1/WAF-1 mediated cell-cycle arrest by RNase L and tristetraprolin, and involvement of AU-rich elements." dans: Nucleic acids research, Vol. 40, Issue 16, pp. 7739-52, (2012) (PubMed).

Al-Ahmadi, Al-Ghamdi, Al-Haj, Al-Saif, Khabar: "Alternative polyadenylation variants of the RNA binding protein, HuR: abundance, role of AU-rich elements and auto-Regulation." dans: Nucleic acids research, Vol. 37, Issue 11, pp. 3612-24, (2009) (PubMed).

Lin, Yu, Chang, Tang, Liao, Lin: "Distinct antiviral roles for human 2',5'-oligoadenylate synthetase family members against dengue virus infection." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 12, pp. 8035-43, (2009) (PubMed).

Han, Townsend, Jha, Paranjape, Silverman, Barton: "A phylogenetically conserved RNA structure in the poliovirus open reading frame inhibits the antiviral endoribonuclease RNase L." dans: Journal of virology, Vol. 81, Issue 11, pp. 5561-72, (2007) (PubMed).

Carpten, Nupponen, Isaacs, Sood, Robbins, Xu, Faruque, Moses, Ewing, Gillanders, Hu, Bujnovszky, Makalowska, Baffoe-Bonnie, Faith, Smith, Stephan, Wiley, Brownstein, Gildea, Kelly, Jenkins, Hostetter et al.: "Germline mutations in the ribonuclease L gene in families showing linkage with HPC1. ..." dans: Nature genetics, Vol. 30, Issue 2, pp. 181-4, (2002) (PubMed).

Wang, Zhou, Vasavada, Dong, Nie, Church, Williams, Banerjee, Silverman: "Elevated levels of 2',5'-linked oligoadenylate-dependent ribonuclease L occur as an early event in colorectal tumorigenesis." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 1, Issue 11, pp. 1421-8, (1999) (PubMed).

Dong, Silverman: "A bipartite model of 2-5A-dependent RNase L." dans: The Journal of biological chemistry, Vol. 272, Issue 35, pp. 22236-42, (1997) (PubMed).

Dong, Silverman: "2-5A-dependent RNase molecules dimerize during activation by 2-5A." dans: The Journal of biological chemistry, Vol. 270, Issue 8, pp. 4133-7, (1995) (PubMed).

Synonymes et noms alternatifs relatifs à RNASEL

ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) (Rnasel), ribonuclease L (RNASEL), E230029I04Rik, PRCA1, RNS4

Protein level used designations for RNASEL

  • 2-5A-dependent RNAase
  • 2-5A-dependent RNase
  • 2-5A-dependent ribonuclease
  • RNase L
  • ribonuclease 4
  • 2',5'-oligoisoadenylate synthetase-dependent
  • interferon-induced 2-5A-dependent RNase
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