RNF111 Produits
(Ring Finger Protein 111 (RNF111))
Catégories
The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012].
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Catégories RNF111 en vedette
RNF111 Anticorps
High quality antibodies with extensive validation data.
RNF111 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
RNF111 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, RNAi
Validations
- (9)
- (5)
N° du produit
ABIN527194
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
- (3)
N° du produit
ABIN527193
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (2)
N° du produit
ABIN6257485
Quantité
100 μL
Fiche technique
Fiche technique
RNF111 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1318194
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3095070
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3136968
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits RNF111
: "The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma." dans: Oncogene, Vol. 35, Issue 27, pp. 3514-23, (2016) (PubMed).: "SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair." dans: Nature communications, Vol. 6, pp. 7499, (2015) (PubMed).
: "Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-? signalling." dans: Nature communications, Vol. 5, pp. 3388, (2014) (PubMed).
: "Multiple Arkadia/RNF111 structures coordinate its Polycomb body association and transcriptional control." dans: Molecular and cellular biology, Vol. 34, Issue 16, pp. 2981-95, (2014) (PubMed).
: "RNF111-dependent neddylation activates DNA damage-induced ubiquitination." dans: Molecular cell, Vol. 49, Issue 5, pp. 897-907, (2013) (PubMed).
: "Arkadia, a novel SUMO-targeted ubiquitin ligase involved in PML degradation." dans: Molecular and cellular biology, Vol. 33, Issue 11, pp. 2163-77, (2013) (PubMed).
: "RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response." dans: The Journal of cell biology, Vol. 201, Issue 6, pp. 797-807, (2013) (PubMed).
: "Efficient TGF-?/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression." dans: Molecular cancer, Vol. 10, Issue 1, pp. 2, (2011) (PubMed).
: "RB1CC1 protein positively regulates transforming growth factor-beta signaling through the modulation of Arkadia E3 ubiquitin ligase activity." dans: The Journal of biological chemistry, Vol. 286, Issue 37, pp. 32502-12, (2011) (PubMed).
: "Context-dependent regulation of the expression of c-Ski protein by Arkadia in human cancer cells." dans: Journal of biochemistry, Vol. 147, Issue 4, pp. 545-54, (2010) (PubMed).
Synonymes et noms alternatifs relatifs à RNF111
ring finger protein 111 (RNF111), ring finger 111 (Rnf111), ring finger protein 111 (Rnf111), ring finger protein 111 (rnf111-b), ring finger protein 111 (rnf111), ARK, ark, Arkadia, MGC81253, MGC146379, RNF111, rnf111Protein level used designations for RNF111
- Arkadia
- E3 ubiquitin-protein ligase Arkadia
- RING finger protein 111
- ring finger 111
- arkadia
- ring finger protein 111
- E3 ubiquitin-protein ligase arkadia-B
- RING finger protein 111-B
- e3 ubiquitin-protein ligase Arkadia-like
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