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RNF111 Produits

(Ring Finger Protein 111 (RNF111))

Catégories

The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012].

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Catégories RNF111 en vedette

RNF111 Anticorps

High quality antibodies with extensive validation data.

RNF111 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

RNF111 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, RNAi
Validations
  • (9)
  • (5)
N° du produit ABIN527194
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
  • (3)
N° du produit ABIN527193
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (2)
N° du produit ABIN6257485
Quantité 100 μL
Fiche technique Fiche technique

RNF111 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1318194
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3095070
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3136968
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits RNF111

Mizutani, Koinuma, Seimiya, Miyazono: "The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma." dans: Oncogene, Vol. 35, Issue 27, pp. 3514-23, (2016) (PubMed).

van Cuijk, van Belle, Turkyilmaz, Poulsen, Janssens, Theil, Sabatella, Lans, Mailand, Houtsmuller, Vermeulen, Marteijn: "SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair." dans: Nature communications, Vol. 6, pp. 7499, (2015) (PubMed).

Zhou, Drabsch, Dekker, de Vinuesa, Li, Hawinkels, Sheppard, Goumans, Luwor, de Vries, Mesker, Tollenaar, Devilee, Lu, Zhu, Zhang, Dijke: "Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-? signalling." dans: Nature communications, Vol. 5, pp. 3388, (2014) (PubMed).

Sun, Liu, Hunter: "Multiple Arkadia/RNF111 structures coordinate its Polycomb body association and transcriptional control." dans: Molecular and cellular biology, Vol. 34, Issue 16, pp. 2981-95, (2014) (PubMed).

Ma, Chen, Zhang, Yang, Wang, Yu: "RNF111-dependent neddylation activates DNA damage-induced ubiquitination." dans: Molecular cell, Vol. 49, Issue 5, pp. 897-907, (2013) (PubMed).

Erker, Neyret-Kahn, Seeler, Dejean, Atfi, Levy: "Arkadia, a novel SUMO-targeted ubiquitin ligase involved in PML degradation." dans: Molecular and cellular biology, Vol. 33, Issue 11, pp. 2163-77, (2013) (PubMed).

Poulsen, Hansen, Wagner, van Cuijk, van Belle, Streicher, Wikström, Choudhary, Houtsmuller, Marteijn, Bekker-Jensen, Mailand: "RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response." dans: The Journal of cell biology, Vol. 201, Issue 6, pp. 797-807, (2013) (PubMed).

Javelaud, van Kempen, Alexaki, Le Scolan, Luo, Mauviel: "Efficient TGF-?/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression." dans: Molecular cancer, Vol. 10, Issue 1, pp. 2, (2011) (PubMed).

Koinuma, Shinozaki, Nagano, Ikushima, Horiguchi, Goto, Chano, Saitoh, Imamura, Miyazono, Miyazawa: "RB1CC1 protein positively regulates transforming growth factor-beta signaling through the modulation of Arkadia E3 ubiquitin ligase activity." dans: The Journal of biological chemistry, Vol. 286, Issue 37, pp. 32502-12, (2011) (PubMed).

Nagano, Koinuma, Miyazawa, Miyazono: "Context-dependent regulation of the expression of c-Ski protein by Arkadia in human cancer cells." dans: Journal of biochemistry, Vol. 147, Issue 4, pp. 545-54, (2010) (PubMed).

Synonymes et noms alternatifs relatifs à RNF111

ring finger protein 111 (RNF111), ring finger 111 (Rnf111), ring finger protein 111 (Rnf111), ring finger protein 111 (rnf111-b), ring finger protein 111 (rnf111), ARK, ark, Arkadia, MGC81253, MGC146379, RNF111, rnf111

Protein level used designations for RNF111

  • Arkadia
  • E3 ubiquitin-protein ligase Arkadia
  • RING finger protein 111
  • ring finger 111
  • arkadia
  • ring finger protein 111
  • E3 ubiquitin-protein ligase arkadia-B
  • RING finger protein 111-B
  • e3 ubiquitin-protein ligase Arkadia-like
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