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RNF20 Produits

(Ring Finger Protein 20 (RNF20))

Catégories

The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012].

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Catégories RNF20 en vedette

RNF20 Anticorps

High quality antibodies with extensive validation data.

RNF20 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

RNF20 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (4)
N° du produit ABIN1327712
Quantité 50 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IF, ICC
Validations
  • (2)
N° du produit ABIN6264788
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
N° du produit ABIN4913698
Quantité 100 μL
Fiche technique Fiche technique

RNF20 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6207367
Quantité 96 tests
Fiche technique Fiche technique

RNF20 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1318333
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3090157
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3135178
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits RNF20

Chen, Jing, Kang, Yang, Wang, Zhang, Zhang, Chen, Chang, Yang, Sun: "Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy." dans: Nucleic acids research, Vol. 45, Issue 3, pp. 1144-1158, (2017) (PubMed).

Chen, Jing, Kang, Yang, Wang, Zhang, Zhang, Chen, Chang, Yang, Sun: "Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy." dans: Nucleic acids research, (2016) (PubMed).

Wu, Chen, Jing, Wang, Men, Zhan, Wang, Gan, Huang, Xie, Mi, Yu, Yu, Chen, Chang, Cai, Chen: "Microarray Analysis Reveals Potential Biological Functions of Histone H2B Monoubiquitination." dans: PLoS ONE, Vol. 10, Issue 7, pp. e0133444, (2015) (PubMed).

Wang, Kawaoka, Yu, Shi, Ni, Yang, Zhu, Roeder, Vakoc: "Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 10, pp. 3901-6, (2013) (PubMed).

Sussman, Stanek, Esteso, Gearhart, Knudsen, McMahon: "The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2)." dans: The Journal of biological chemistry, Vol. 288, Issue 33, pp. 24234-46, (2013) (PubMed).

Hahn, Dickson, Jackson, Clarkson, Gill, Marsh: "The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination." dans: Human molecular genetics, Vol. 21, Issue 3, pp. 559-68, (2012) (PubMed).

Jääskeläinen, Makkonen, Visakorpi, Kim, Roeder, Palvimo: "Histone H2B ubiquitin ligases RNF20 and RNF40 in androgen signaling and prostate cancer cell growth." dans: Molecular and cellular endocrinology, Vol. 350, Issue 1, pp. 87-98, (2012) (PubMed).

Arora, Zhang, Heine, Ozer, Liu, Huang, Parvin: "Promoters active in interphase are bookmarked during mitosis by ubiquitination." dans: Nucleic acids research, Vol. 40, Issue 20, pp. 10187-202, (2012) (PubMed).

Kim, Roeder: "Nucleosomal H2B ubiquitylation with purified factors." dans: Methods (San Diego, Calif.), Vol. 54, Issue 3, pp. 331-8, (2011) (PubMed).

Taniue, Oda, Hayashi, Okuno, Akiyama: "A member of the ETS family, EHF, and the ATPase RUVBL1 inhibit p53-mediated apoptosis." dans: EMBO reports, Vol. 12, Issue 7, pp. 682-9, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à RNF20

ring finger protein 20 (RNF20), ring finger protein 20 (Rnf20), 4833430L21Rik, AW540162, BRE1, BRE1A, C79397, hBRE1, mKIAA4116

Protein level used designations for RNF20

  • BRE1-A
  • E3 ubiquitin-protein ligase BRE1A
  • BRE1 E3 ubiquitin ligase homolog
  • homolog of S. cerevisiae BRE1
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