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ROBO1 Produits

(Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))
Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].

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Catégories ROBO1 en vedette

ROBO1 Anticorps

High quality antibodies with extensive validation data.

ROBO1 Kits ELISA

Reliable ELISA kits for a wide range of species.

ROBO1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ROBO1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IP
Validations
  • (1)
  • (5)
N° du produit ABIN129621
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (10)
N° du produit ABIN185537
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (3)
N° du produit ABIN7270110
Quantité 100 μL
Fiche technique Fiche technique

ROBO1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6973548
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959204
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6730772
Quantité 96 tests
Fiche technique Fiche technique

ROBO1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1318424
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN6964317
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2731104
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits ROBO1

Fernando, Grisolia, Lu, Atkins, Smith: "Slit2 Modulates the Inflammatory Phenotype of Orbit-Infiltrating Fibrocytes in Graves' Disease." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 12, pp. 3942-3949, (2018) (PubMed).

Zhou, Thiery: "Loss of Git2 induces epithelial-mesenchymal transition by miR146a-Cnot6L-controlled expression of Zeb1." dans: Journal of cell science, Vol. 126, Issue Pt 12, pp. 2740-6, (2013) (PubMed).

Zhou, Geng, Chi, Zhang, Niu, Lan, Ma, Yang, Wang, Ding, Geng: "Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis." dans: Cell research, Vol. 21, Issue 4, pp. 609-26, (2011) (PubMed).

Andrews, Liapi, Plachez, Camurri, Zhang, Mori, Murakami, Parnavelas, Sundaresan, Richards: "Robo1 regulates the development of major axon tracts and interneuron migration in the forebrain." dans: Development (Cambridge, England), Vol. 133, Issue 11, pp. 2243-52, (2006) (PubMed).

Li, Wang, Chen, Liang: "[Auditory neuropathy in children(analysis of 14 cases)]." dans: Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, Vol. 19, Issue 1, pp. 19-21, (2006) (PubMed).

Hannula-Jouppi, Kaminen-Ahola, Taipale, Eklund, Nopola-Hemmi, Kääriäinen, Kere: "The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia." dans: PLoS genetics, Vol. 1, Issue 4, pp. e50, (2005) (PubMed).

Wang, Xiao, Ding, Zhang, Yuan, Gui, Qian, Duan, Chen, Rao, Geng: "Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity." dans: Cancer cell, Vol. 4, Issue 1, pp. 19-29, (2003) (PubMed).

Latil, Chêne, Cochant-Priollet, Mangin, Fournier, Berthon, Cussenot: "Quantification of expression of netrins, slits and their receptors in human prostate tumors." dans: International journal of cancer. Journal international du cancer, Vol. 103, Issue 3, pp. 306-15, (2002) (PubMed).

Hivert, Liu, Chuang, Doherty, Sundaresan: "Robo1 and Robo2 are homophilic binding molecules that promote axonal growth." dans: Molecular and cellular neurosciences, Vol. 21, Issue 4, pp. 534-45, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à ROBO1

roundabout guidance receptor 1 (ROBO1), roundabout guidance receptor 1 (Robo1), roundabout, axon guidance receptor, homolog 1 (Drosophila) (robo1), roundabout guidance receptor 1 L homeolog (robo1.L), roundabout guidance receptor 1 (robo1), AW494633, AW742721, DUTT1, dutt1, Gm310, MGC122264, ROBO1, roundabout, roundabout-1, SAX3, sax3

Protein level used designations for ROBO1

  • deleted in U twenty twenty
  • roundabout homolog 1
  • roundabout (axon guidance receptor, Drosophila) homolog 1
  • roundabout, axon guidance receptor, homolog 1 (Drosophila)
  • Roundabout1 protein
  • roundabout-1
  • roundabout 1
  • roundabout, axon guidance receptor, homolog 1
  • roundabout homolog 1-like
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