Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

ROBO3 Produits

(Roundabout, Axon Guidance Receptor, Homolog 3 (ROBO3))

Catégories

This gene is a member of the Roundabout (ROBO) gene family that controls neurite outgrowth, growth cone guidance, and axon fasciculation. ROBO proteins are a subfamily of the immunoglobulin transmembrane receptor superfamily. SLIT proteins 1-3, a family of secreted chemorepellants, are ligands for ROBO proteins and SLIT/ROBO interactions regulate myogenesis, leukocyte migration, kidney morphogenesis, angiogenesis, and vasculogenesis in addition to neurogenesis. This gene, ROBO3, has a putative extracellular domain with five immunoglobulin (Ig)-like loops and three fibronectin (Fn) type III motifs, a transmembrane segment, and a cytoplasmic tail with three conserved signaling motifs: CC0, CC2, and CC3 (CC for conserved cytoplasmic). Unlike other ROBO family members, ROBO3 lacks motif CC1. The ROBO3 gene regulates axonal navigation at the ventral midline of the neural tube. In mouse, loss of Robo3 results in a complete failure of commissural axons to cross the midline throughout the spinal cord and the hindbrain. Mutations ROBO3 result in horizontal gaze palsy with progressive scoliosis (HGPPS)\; an autosomal recessive disorder characterized by congenital absence of horizontal gaze, progressive scoliosis, and failure of the corticospinal and somatosensory axon tracts to cross the midline in the medulla. Alternative transcript variants have been described but have not been experimentally validated. [provided by RefSeq, Dec 2009].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories ROBO3 en vedette

ROBO3 Anticorps

High quality antibodies with extensive validation data.

ROBO3 Kits ELISA

Reliable ELISA kits for a wide range of species.

ROBO3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ROBO3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, WB
Validations
  • (3)
N° du produit ABIN528582
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, WB
Validations
  • (1)
  • (1)
N° du produit ABIN190793
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
N° du produit ABIN7168446
Quantité 100 μL
Fiche technique Fiche technique

ROBO3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN4884368
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
N° du produit ABIN6384942
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6730276
Quantité 96 tests
Fiche technique Fiche technique

ROBO3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1318429
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Cow, Human, Monkey, Panda
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2751303
Quantité 5 applications
Fiche technique Fiche technique

Dernières publications sur nos produits ROBO3

Bauer, Dowejko, Bosserhoff, Reichert, Bauer: "Slit-2 facilitates interaction of P-cadherin with Robo-3 and inhibits cell migration in an oral squamous cell carcinoma cell line." dans: Carcinogenesis, Vol. 32, Issue 6, pp. 935-43, (2011) (PubMed).

Kato, Takeuchi, Sato, Yoneyama, Yamamoto, Matsui, Uematsu, Jung, Kawai, Ishii, Yamaguchi, Otsu, Tsujimura, Koh, Reis e Sousa, Matsuura, Fujita, Akira: "Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses." dans: Nature, Vol. 441, Issue 7089, pp. 101-5, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à ROBO3

roundabout guidance receptor 3 (ROBO3), roundabout 3 (robo3), roundabout guidance receptor 3 (Robo3), robo3 (LOC658818), roundabout guidance receptor 3 L homeolog (robo3.L), roundabout, axon guidance receptor, homolog 3 (Drosophila) (robo3), cb503, CG5423, CG14345, CT17158, DKFZp468G0223, DmelCG5423, dRobo-3, HGPPS, HGPS, RBIG1, Rbig1, Rig-1, RIG1, Rig1, Robo-3, Robo3, ROBO3, robo3, Robo3a, Robo3b

Protein level used designations for ROBO3

  • retinoblastoma inhibiting gene 1
  • roundabout homolog 3
  • roundabout-like protein 3
  • robo3
  • CG5423-PA
  • robo3-PA
  • roundabout, axon guidance receptor, homolog 3
  • roundabout, axon guidance receptor, homolog 3 (Drosophila)
  • GLEAN_06743
  • roundabout 3
  • roundabout homolog 3-like
  • retinoblastoma-inhibiting gene 1 protein
  • roundabout (axon guidance receptor, Drosophila) homolog 3
  • twi
  • twitch twice
Vous êtes ici:
Support technique