ROR1 Produits
(Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
Catégories
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012].
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Catégories ROR1 en vedette
ROR1 Anticorps
High quality antibodies with extensive validation data.
ROR1 Kits ELISA
Reliable ELISA kits for a wide range of species.
ROR1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ROR1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7439615
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, FACS, IHC (p)
Validations
- (5)
N° du produit
ABIN392043
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, FACS
Validations
- (8)
N° du produit
ABIN3032439
Quantité
0.2 mL
Fiche technique
Fiche technique
ROR1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959062
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4886267
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4884374
Quantité
96 tests
Fiche technique
Fiche technique
ROR1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Cynomolgus, Human, Rhesus Monkey
Source
HEK-293 Cells
Validations
- (5)
N° du produit
ABIN7275532
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cynomolgus, Human, Rhesus Monkey
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275530
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cynomolgus, Human, Rhesus Monkey
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275527
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ROR1
: "ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma." dans: Oncogene, Vol. 38, Issue 26, pp. 5142-5157, (2019) (PubMed).: "Interaction between ROR1 and MuSK activation complex in myogenic cells." dans: FEBS letters, Vol. 592, Issue 3, pp. 434-445, (2019) (PubMed).
: "Antibody-drug conjugate T-DM1 treatment for HER2+ breast cancer induces ROR1 and confers resistance through activation of Hippo transcriptional coactivator YAP1." dans: EBioMedicine, Vol. 43, pp. 211-224, (2019) (PubMed).
: "Deep Mining of Complex Antibody Phage Pools Generated by Cell Panning Enables Discovery of Rare Antibodies Binding New Targets and Epitopes." dans: Frontiers in pharmacology, Vol. 10, pp. 847, (2019) (PubMed).
: "Silencing ROR1 and ROR2 inhibits invasion and adhesion in an organotypic model of ovarian cancer metastasis." dans: Oncotarget, Vol. 8, Issue 68, pp. 112727-112738, (2018) (PubMed).
: "Maintenance and pharmacologic targeting of ROR1 protein levels via UHRF1 in t(1;19) pre-B-ALL." dans: Oncogene, Vol. 37, Issue 38, pp. 5221-5232, (2018) (PubMed).
: "A receptor tyrosine kinase ROR1 inhibitor (KAN0439834) induced significant apoptosis of pancreatic cells which was enhanced by erlotinib and ibrutinib." dans: PLoS ONE, Vol. 13, Issue 6, pp. e0198038, (2018) (PubMed).
: "ROR1 and ROR2 play distinct and opposing roles in endometrial cancer." dans: Gynecologic oncology, Vol. 148, Issue 3, pp. 576-584, (2018) (PubMed).
: "ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1." dans: Nature communications, Vol. 7, pp. 10060, (2016) (PubMed).
: "Spontaneous Immunity Against the Receptor Tyrosine Kinase ROR1 in Patients with Chronic Lymphocytic Leukemia." dans: PLoS ONE, Vol. 10, Issue 11, pp. e0142310, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à ROR1
receptor tyrosine kinase like orphan receptor 1 (ROR1), receptor tyrosine kinase-like orphan receptor 1 (Ror1), receptor tyrosine kinase like orphan receptor 1 (Ror1), receptor tyrosine kinase-like orphan receptor 1 (ror1), 2810404D04Rik, dJ537F10.1, fi34e02, mRor1, NTRKR1, Ntrkr1, RGD1559469, ROR1, si:dkey-209n16.1, wu:fi34e02Protein level used designations for ROR1
- neurotrophic tyrosine kinase, receptor-related 1
- tyrosine-protein kinase transmembrane receptor ROR1
- neurotrophic tyrosine kinase, receptor related 1
- tyrosine kinase orphan receptor 1
- receptor tyrosine kinase-like orphan receptor 1
- tyrosine-protein kinase transmembrane receptor ROR1-like
- inactive tyrosine-protein kinase transmembrane receptor ROR1
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