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RORA Produits

(RAR-Related Orphan Receptor A (RORA))

Catégories

The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Catégories RORA en vedette

RORA Anticorps

High quality antibodies with extensive validation data.

RORA Kits ELISA

Reliable ELISA kits for a wide range of species.

RORA Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

RORA recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF, FACS
Validations
  • (4)
N° du produit ABIN387939
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (2)
  • (3)
N° du produit ABIN2857022
Quantité 100 μL
Fiche technique Fiche technique

Application WB
Validations
  • (1)
  • (4)
N° du produit ABIN2776008
Quantité 100 μL
Fiche technique Fiche technique

RORA recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6959046
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5658351
Quantité 96 tests
Fiche technique Fiche technique

RORA recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1318456
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1318454
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7405298
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits RORA

Yasui, Matsuzaki, Konno, Hirai: "Global Knockdown of Retinoid-related Orphan Receptor α in Mature Purkinje Cells Reveals Aberrant Cerebellar Phenotypes of Spinocerebellar Ataxia." dans: Neuroscience, (2020) (PubMed).

Luo, Wang, Yeh, Sun, Liang, Xiao, Xu, Niu, Cheng, Maity, Jiang, Chang: "LncRNA-p21 alters the antiandrogen enzalutamide-induced prostate cancer neuroendocrine differentiation via modulating the EZH2/STAT3 signaling." dans: Nature communications, Vol. 10, Issue 1, pp. 2571, (2019) (PubMed).

Brożyna, Jóźwicki, Skobowiat, Jetten, Slominski: "RORα and RORγ expression inversely correlates with human melanoma progression." dans: Oncotarget, Vol. 7, Issue 39, pp. 63261-63282, (2018) (PubMed).

Strzelczyk, Gołąbek, Cuber, Krakowczyk, Owczarek, Fronczek, Choręża, Hudziec, Ostrowska: "Comparison of Selected Protein Levels in Tumour and Surgical Margin in a Group of Patients with Oral Cavity Cancer." dans: Biochemical genetics, Vol. 55, Issue 4, pp. 322-334, (2017) (PubMed).

Suyama, Silagi, Choi, Sakabe, Mochida, Shapiro, Risbud: "Circadian factors BMAL1 and RORα control HIF-1α transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health." dans: Oncotarget, Vol. 7, Issue 17, pp. 23056-71, (2016) (PubMed).

Li, Ying, Tong, Zhong, Su, Xiang, Shu, Rong, Xiong, Li, Chan, Ambinder, Guo, Tao: "Epigenetic identification of receptor tyrosine kinase-like orphan receptor 2 as a functional tumor suppressor inhibiting β-catenin and AKT signaling but frequently methylated in common carcinomas." dans: Cellular and molecular life sciences : CMLS, Vol. 71, Issue 11, pp. 2179-92, (2014) (PubMed).

Barrett, Fang, Gargano, Markovich, Kocarek, Runge-Morris: "Regulation of murine hepatic hydroxysteroid sulfotransferase expression in hyposulfatemic mice and in a cell model of 3'-phosphoadenosine-5'-phosphosulfate deficiency." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 41, Issue 8, pp. 1505-13, (2013) (PubMed).

Benderdour, Fahmi, Beaudet, Fernandes, Shi: "Nuclear receptor retinoid-related orphan receptor α1 modulates the metabolic activity of human osteoblasts." dans: Journal of cellular biochemistry, Vol. 112, Issue 8, pp. 2160-9, (2011) (PubMed).

Tordjman, Leroyer, Chauvet, Quette, Chauvet, Tomkiewicz, Chapron, Barouki, Forest, Aggerbeck, Antoine: "Cytosolic aspartate aminotransferase, a new partner in adipocyte glyceroneogenesis and an atypical target of thiazolidinedione." dans: The Journal of biological chemistry, Vol. 282, Issue 32, pp. 23591-602, (2007) (PubMed).

Lechtken, Hörnig, Werz, Corvey, Zündorf, Dingermann, Brandes, Steinhilber: "Extracellular signal-regulated kinase-2 phosphorylates RORalpha4 in vitro." dans: Biochemical and biophysical research communications, Vol. 358, Issue 3, pp. 890-6, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à RORA

RAR related orphan receptor A (RORA), RAR related orphan receptor A (rora), RAR-related orphan receptor A (Rora), RAR-related orphan receptor A, paralog a (roraa), RAR-related orphan receptor alpha (Rora), 9530021D13Rik, gb:dq017624, MGC146531, nmf267, nr1f1, NR1F1, Nr1f1, ror1, ROR1, ror2, ROR2, ror3, ROR3, rora2, RORalpha-B, RORalpha1, RZR-ALPHA, rzra, RZRA, sg, staggerer, tmgc26

Protein level used designations for RORA

  • nuclear receptor ROR-alpha
  • RAR-related orphan receptor A
  • RAR-related orphan receptor alpha
  • ROR-alpha
  • nuclear receptor RZR-alpha
  • nuclear receptor subfamily 1 group F member 1
  • retinoic acid receptor-related orphan receptor alpha
  • retinoid-related orphan receptor alpha
  • thyroid hormone nuclear receptor alpha variant 4
  • transcription factor RZR-alpha
  • NR1F1-B
  • retinoid-related orphan receptor alpha 2
  • rora
  • retinoid-related orphan receptor-alpha
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