RPA1 Produits
(Replication Protein A1, 70kDa (RPA1))
Catégories
Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair\; it does not support chromosomal DNA replication and cell cycle progression through S- phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. Plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing.
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Catégories RPA1 en vedette
RPA1 Anticorps
High quality antibodies with extensive validation data.
RPA1 Kits ELISA
Reliable ELISA kits for a wide range of species.
RPA1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
RPA1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Monkey
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (1)
- (7)
N° du produit
ABIN969564
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IP, IHC (p), ICC
Validations
- (7)
N° du produit
ABIN2856633
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF, FACS
Validations
- (7)
N° du produit
ABIN1500741
Quantité
100 μL
Fiche technique
Fiche technique
RPA1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959123
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959124
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4972520
Quantité
96 tests
Fiche technique
Fiche technique
RPA1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124825
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1318500
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7408951
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits RPA1
: "The nuclear DEK interactome supports multi-functionality." dans: Proteins, Vol. 86, Issue 1, pp. 88-97, (2018) (PubMed).: "ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress." dans: Cell, Vol. 158, Issue 3, pp. 633-46, (2014) (PubMed).
: "RPA coordinates DNA end resection and prevents formation of DNA hairpins." dans: Molecular cell, Vol. 50, Issue 4, pp. 589-600, (2013) (PubMed).
: "MRX protects fork integrity at protein-DNA barriers, and its absence causes checkpoint activation dependent on chromatin context." dans: Nucleic acids research, Vol. 41, Issue 5, pp. 3173-89, (2013) (PubMed).
: "Phenothiazine Inhibitors of TLKs Affect Double-Strand Break Repair and DNA Damage Response Recovery and Potentiate Tumor Killing with Radiomimetic Therapy." dans: Genes & cancer, Vol. 4, Issue 1-2, pp. 39-53, (2013) (PubMed).
: "Mechanism of release and fate of excised oligonucleotides during nucleotide excision repair." dans: The Journal of biological chemistry, Vol. 287, Issue 27, pp. 22889-99, (2012) (PubMed).
: "In vitro analysis of the role of replication protein A (RPA) and RPA phosphorylation in ATR-mediated checkpoint signaling." dans: The Journal of biological chemistry, Vol. 287, Issue 43, pp. 36123-31, (2012) (PubMed).
: "The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA." dans: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19237-46, (2011) (PubMed).
: "Role of interaction of XPF with RPA in nucleotide excision repair." dans: Journal of molecular biology, Vol. 413, Issue 2, pp. 337-46, (2011) (PubMed).
: "Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation." dans: Molecular and cellular biology, Vol. 30, Issue 6, pp. 1382-96, (2010) (PubMed).
Synonymes et noms alternatifs relatifs à RPA1
replication protein A1 (RPA1), replication protein A1 (Rpa1), replication protein A1 (rpa1), replication protein A1, 70kDa (RPA1), replication protein A1 L homeolog (rpa1.L), Replication Protein A 70 (RpA-70), 70kDa, 5031405K23Rik, AA589576, AW557552, Cb1-727, CG9633, D-RPA70, D-SSB, Dmel\\CG9633, DmRPA, dmrpa1, DRP-A, dRP-A, HSSB, hssb, i164, LOC100230990, MST075, mst075, REPA1, repa1, RF-A, rf-a, RP-A, rp-a, rpa, Rpa, RPA, Rpa-70, RPA1, RPA70, rpa70, RPA 70, RpA70, RPA 70 kDa, Ssb-70, wu:fi14b08, zgc:55337, zgc:77092Protein level used designations for RPA1
- MSTP075
- RF-A protein 1
- RP-A p70
- replication factor A protein 1
- replication protein A 70 kDa DNA-binding subunit
- single-stranded DNA-binding protein
- replication protein A1, 70kDa
- replication protein A1
- replication protein A 70 kDa DNA-binding subunit-like
- replication protein A (RPA)
- CG9633-PA
- RpA-70-PA
- drosophila replication protein A
- replication protein A 70
- single stranded-binding protein 70
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