Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008].
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Knight, Tian, Lee, Wang, Beauvais, Zou, Megeney, Gingras, Pawson, Figeys, Kothary: "A novel whole-cell lysate kinase assay identifies substrates of the p38 MAPK in differentiating myoblasts." dans: Skeletal muscle, Vol. 2, pp. 5, (2012) (PubMed).
Fernandez-Pol, Klos, Hamilton: "A growth factor-inducible gene encodes a novel nuclear protein with zinc finger structure." dans: The Journal of biological chemistry, Vol. 268, Issue 28, pp. 21198-204, (1993) (PubMed).
Synonymes et noms alternatifs relatifs à RPS27
ribosomal protein S27 (RPS27), ribosomal protein S27 (Rps27), 40S ribosomal protein S27 (LOC726295), ribosomal protein S27 pseudogene (RPS27P), 40S ribosomal protein S27 (rps27), Ribosomal protein S27, component of cytosolic 80S ribosome and 40S small subunit (RPS27), component of 80S ribosome and 40S small subunit (rps27), ribosomal protein S27 L homeolog (rps27.L), 40S ribosomal protein S27 (rps-27), 3200001M24Rik, DDBDRAFT_0203425, DDBDRAFT_0231065, DDB_0203425, DDB_0231065, GB13072, MPS-1, mps-1, MPS1, mps1, S27
Protein level used designations for RPS27
40S ribosomal protein S27
metallopan-stimulin 1
metallopanstimulin 1
ribosomal protein S27 (metallopanstimulin 1)
Ribosomal protein S27, component of cytosolic 80S ribosome and 40S small subunit