RRM1 Produits
(Ribonucleotide Reductase M1 (RRM1))
Catégories
This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq, Jul 2008].
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Catégories RRM1 en vedette
RRM1 Anticorps
High quality antibodies with extensive validation data.
RRM1 Kits ELISA
Reliable ELISA kits for a wide range of species.
RRM1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
RRM1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (7)
N° du produit
ABIN7193575
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (7)
N° du produit
ABIN3021563
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7436186
Quantité
100 μL
Fiche technique
Fiche technique
RRM1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969958
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959185
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959186
Quantité
96 tests
Fiche technique
Fiche technique
RRM1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1318900
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1318898
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7408315
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits RRM1
: "Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)." dans: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 107, (2018) (PubMed).: "Bcl2 induces DNA replication stress by inhibiting ribonucleotide reductase." dans: Cancer research, Vol. 74, Issue 1, pp. 212-23, (2014) (PubMed).
: "The effect of the acid-sensitivity of 4-(N)-stearoyl gemcitabine-loaded micelles on drug resistance caused by RRM1 overexpression." dans: Biomaterials, Vol. 34, Issue 9, pp. 2327-39, (2013) (PubMed).
: "Stearoyl gemcitabine nanoparticles overcome resistance related to the over-expression of ribonucleotide reductase subunit M1." dans: Journal of controlled release : official journal of the Controlled Release Society, Vol. 157, Issue 1, pp. 132-40, (2012) (PubMed).
: "Silencing of ribonucleotide reductase subunit M1 potentiates the antitumor activity of gemcitabine in resistant cancer cells." dans: Cancer biology & therapy, Vol. 13, Issue 10, pp. 908-14, (2012) (PubMed).
: "Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection." dans: Molecular human reproduction, Vol. 16, Issue 10, pp. 770-7, (2010) (PubMed).
: "A Large-scale genetic association study of esophageal adenocarcinoma risk." dans: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).
Synonymes et noms alternatifs relatifs à RRM1
ribonucleotide reductase catalytic subunit M1 (RRM1), Ribonucleoside diphosphate reductase large subunit (RnrL), ribonucleoside-diphosphate reductase large subunit (LOC100472317), ribonucleotide reductase catalytic subunit M1 (rrm1), ribonucleotide reductase M1 L homeolog (rrm1.L), ribonucleotide reductase M1 (Rrm1), ribonucleotide reductase catalytic subunit M1 (Rrm1), ribonucleotide reductase M1 (RRM1), ribonucleotide reductase M1 polypeptide (rrm1), cb396, cb838, CG5371, CHUNP6866, Dmel\\CG5371, DmRNR1, l(2)k06709, R1, r1, RIR1, RNR1, RnrM1, RntL, RR1, sb:cb548, wu:fb39b07, wu:fi14b02, wu:fk95f07, XRRM1Protein level used designations for RRM1
- ribonucleoside diphosphate reductase large subunit
- CG5371-PA
- RnrL-PA
- ribonucleoside diphosphate reductase M1 subunit
- ribonucleoside-diphosphate reductase large subunit
- ribonucleoside-diphosphate reductase M1 chain
- ribonucleotide reductase M1 polypeptide
- ribonucleotide reductase M1
- ribonucleoside-diphosphate reductase large subunit-like
- ribonucleoside-diphosphate reductase subunit M1
- ribonucleotide reductase, R1 subunit
- ribonucleotide reductase large subunit
- ribonucleotide reductase protein r1 class I
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