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RRM2 Produits

(Ribonucleotide Reductase M2 (RRM2))

Catégories

This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Sep 2009].

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Catégories RRM2 en vedette

RRM2 Anticorps

High quality antibodies with extensive validation data.

RRM2 Kits ELISA

Reliable ELISA kits for a wide range of species.

RRM2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

RRM2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, IP, IHC (p)
Validations
  • (5)
  • (6)
N° du produit ABIN562744
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (1)
  • (3)
N° du produit ABIN2855573
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (4)
N° du produit ABIN6147265
Quantité 100 μL
Fiche technique Fiche technique

RRM2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
N° du produit ABIN6969960
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969959
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1155808
Quantité 96 tests
Fiche technique Fiche technique

RRM2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN667014
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1318902
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1318904
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits RRM2

Xia, Wang, Song, Meng, Huang, Huang: "Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)." dans: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 107, (2018) (PubMed).

Castelblanco, Zafon, Maravall, Gallel, Martinez, Capel, Bella, Halperin, Temprana, Iglesias, Puig-Domingo, Robledo, Matias-Guiu, Mauricio: "APLP2, RRM2, and PRC1: New Putative Markers for the Differential Diagnosis of Thyroid Follicular Lesions." dans: Thyroid : official journal of the American Thyroid Association, Vol. 27, Issue 1, pp. 59-66, (2016) (PubMed).

Xu, Li, Tao, Li, Fang, Zhao, Li, Li, Wang, Feng, Pan: "Histone acetyltransferase inhibitor II induces apoptosis in glioma cell lines via the p53 signaling pathway." dans: Journal of experimental & clinical cancer research : CR, Vol. 33, pp. 108, (2015) (PubMed).

Su, Wu, Ko, Tsai, Tee, Chien, Chou, Lin, Low, Chou, Yang, Wang: "The expression of ribonucleotide reductase M2 in the carcinogenesis of uterine cervix and its relationship with clinicopathological characteristics and prognosis of cancer patients." dans: PLoS ONE, Vol. 9, Issue 3, pp. e91644, (2015) (PubMed).

Kim, Park, Joo, Shen, Hong, Kim, Singh, Lee, Shin: "RRM1 maintains centrosomal integrity via CHK1 and CDK1 signaling during replication stress." dans: Cancer letters, Vol. 346, Issue 2, pp. 249-56, (2014) (PubMed).

Lane, Yu, Lackey, Chen, Marzluff, Cook: "Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins." dans: PLoS ONE, Vol. 8, Issue 3, pp. e58456, (2013) (PubMed).

Yoshida, Tsunoda, Doi, Tanaka, Fujimoto, Machida, Ota, Koyanagi, Takashima, Sasazuki, Kuroki, Iwasaki, Shirasawa: "KRAS-mediated up-regulation of RRM2 expression is essential for the proliferation of colorectal cancer cell lines." dans: Anticancer research, Vol. 31, Issue 7, pp. 2535-9, (2011) (PubMed).

Zhou, Snyder, Lieberman: "Epstein-Barr virus episome stability is coupled to a delay in replication timing." dans: Journal of virology, Vol. 83, Issue 5, pp. 2154-62, (2009) (PubMed).

Tang, Deng, Wang, Dai, Wang, Jiang, Li, Li, Sheng, Wu, Li, Zeng et al.: "Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in ..." dans: Molecular & cellular proteomics : MCP, Vol. 6, Issue 11, pp. 1952-67, (2007) (PubMed).

Takada, Shibata, Hiraoka, Masuda: "Identification of ribonucleotide reductase protein R1 as an activator of microtubule nucleation in Xenopus egg mitotic extracts." dans: Molecular biology of the cell, Vol. 11, Issue 12, pp. 4173-87, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à RRM2

ribonucleotide reductase regulatory subunit M2 (RRM2), ribonucleotide reductase M2 (Rrm2), ribonucleotide reductase regulatory subunit M2 (Rrm2), ribonucleotide reductase M2, gene 2 L homeolog (rrm2.2.L), ribonucleotide reductase M2, gene 1 (rrm2.1), ribonucleotide reductase regulatory subunit M2 (rrm2), ribonucleotide reductase M2 polypeptide (rrm2), AA407299, cb111, chunp6884, R2, r2, RR2, RR2M, rr2m, rrm2

Protein level used designations for RRM2

  • ribonucleoside-diphosphate reductase subunit M2
  • ribonucleotide reductase M2 polypeptide
  • ribonucleotide reductase small chain
  • ribonucleotide reductase small subunit
  • ribonucleoside-diphosphate reductase M2 chain
  • Ribonucleotide reductase 2
  • etID309896.20
  • reductase M2 polypeptide variant 1
  • reductase M2 polypeptide variant 2
  • reductase M2 polypeptide variant 3a
  • reductase M2 polypeptide variant 3b
  • reductase M2 polypeptide variant 3c
  • reductase M2 polypeptide variant 3d
  • ribonucleotide reductase protein r2 class I
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