RUNX1T1 Produits
(Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
Catégories
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8\;21)(q22\;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010].
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Catégories RUNX1T1 en vedette
RUNX1T1 Anticorps
High quality antibodies with extensive validation data.
RUNX1T1 Kits ELISA
Reliable ELISA kits for a wide range of species.
RUNX1T1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
RUNX1T1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, ChIP
Validations
- (6)
N° du produit
ABIN6655575
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
N° du produit
ABIN560190
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
N° du produit
ABIN7165188
Quantité
100 μg
Fiche technique
Fiche technique
RUNX1T1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969697
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1150734
Quantité
96 tests
Fiche technique
Fiche technique
RUNX1T1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1318994
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1318996
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3093943
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits RUNX1T1
: "Sperm chromatin proteomics identifies evolutionarily conserved fertility factors." dans: Nature, Vol. 443, Issue 7107, pp. 101-5, (2006) (PubMed).: "RNA helicases: regulators of differentiation." dans: Clinical biochemistry, Vol. 38, Issue 6, pp. 499-503, (2005) (PubMed).
: "Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity. ..." dans: Nature biotechnology, Vol. 23, Issue 3, pp. 344-8, (2005) (PubMed).
: "The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cells." dans: BMC cancer, Vol. 4, pp. 44, (2004) (PubMed).
: "VASA is a specific marker for both normal and malignant human germ cells." dans: Laboratory investigation; a journal of technical methods and pathology, Vol. 82, Issue 2, pp. 159-66, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (runx1t1), RUNX1 translocation partner 1 L homeolog (runx1t1.L), RUNX1 translocation partner 1 (RUNX1T1), runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (Runx1t1), RUNX1 translocation partner 1 (Runx1t1), AML1T1, CBFA2T1, Cbfa2t1, Cbfa2t1h, CDR, ETO, MTG8, si:ch211-232j17.1, wu:fi14b07, zgc:154044, ZMYND2Protein level used designations for RUNX1T1
- protein CBFA2T1
- MTG8
- MTG8/ETOb
- expressed during postmitotic spinal neurons, most likely in motorneurons
- acute myelogenous leukemia 1 translocation 1, cyclin-D related
- core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related
- eight twenty one protein
- myeloid translocation gene on 8q22
- zinc finger MYND domain-containing protein 2
- CBFA2T1 identified gene homolog
- acute myelogenous leukemia 1 translocation 1 protein
- core-binding factor, runt domain, alpha subunit 2
- cyclin D-related
- translocated to, 1
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