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SAE1 Produits

(SUMO1 Activating Enzyme Subunit 1 (SAE1))

Catégories

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010].

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Catégories SAE1 en vedette

SAE1 Anticorps

High quality antibodies with extensive validation data.

SAE1 Kits ELISA

Reliable ELISA kits for a wide range of species.

SAE1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SAE1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (1)
  • (5)
N° du produit ABIN564342
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p), ICC, IP
Validations
  • (7)
N° du produit ABIN2856922
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (4)
N° du produit ABIN389081
Quantité 400 μL
Fiche technique Fiche technique

SAE1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970456
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380924
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6951062
Quantité 96 tests
Fiche technique Fiche technique

SAE1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125243
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1319108
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2131704
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SAE1

Kho, Lee, Jeong, Oh, Gorski, Fish, Sanchez, DeVita, Christensen, Dahl, Hajjar: "Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure." dans: Nature communications, Vol. 6, pp. 7229, (2015) (PubMed).

Fujimoto, Matsushita, Hamaguchi, Kaji, Asano, Ogawa, Yamaoka, Fujikawa, Tsukada, Sato, Echigo, Hasegawa, Takehara: "Autoantibodies to small ubiquitin-like modifier activating enzymes in Japanese patients with dermatomyositis: comparison with a UK Caucasian cohort." dans: Annals of the rheumatic diseases, Vol. 72, Issue 1, pp. 151-3, (2012) (PubMed).

Lois, Lima: "Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1." dans: The EMBO journal, Vol. 24, Issue 3, pp. 439-51, (2005) (PubMed).

Desterro, Rodriguez, Kemp, Hay: "Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1." dans: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 10618-24, (1999) (PubMed).

Norton, Atherton: "Coupling of cell growth control and apoptosis functions of Id proteins." dans: Molecular and cellular biology, Vol. 18, Issue 4, pp. 2371-81, (1998) (PubMed).

Norton, Deed, Craggs, Sablitzky: "Id helix-loop-helix proteins in cell growth and differentiation." dans: Trends in cell biology, Vol. 8, Issue 2, pp. 58-65, (1998) (PubMed).

Cooper, Brady, Bilia, Iscove, Quesenberry: "Expression of the Id family helix-loop-helix regulators during growth and development in the hematopoietic system." dans: Blood, Vol. 89, Issue 9, pp. 3155-65, (1997) (PubMed).

Hara, Hall, Peters: "Cdk2-dependent phosphorylation of Id2 modulates activity of E2A-related transcription factors." dans: The EMBO journal, Vol. 16, Issue 2, pp. 332-42, (1997) (PubMed).

Langlands, Yin, Anand, Prochownik: "Differential interactions of Id proteins with basic-helix-loop-helix transcription factors." dans: The Journal of biological chemistry, Vol. 272, Issue 32, pp. 19785-93, (1997) (PubMed).

Iavarone, Garg, Lasorella, Hsu, Israel: "The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein." dans: Genes & development, Vol. 8, Issue 11, pp. 1270-84, (1994) (PubMed).

Synonymes et noms alternatifs relatifs à SAE1

SUMO1 activating enzyme subunit 1 (SAE1), SUMO1 activating enzyme subunit 1 (Sae1), SUMO1 activating enzyme subunit 1 L homeolog (sae1.L), SUMO1 activating enzyme subunit 1 (sae1), 2400010M20Rik, 2610044L12Rik, AL033372, aos, AOS1, Aos1p, AW743391, D7Ertd177e, HSPC140, sae2a, SUA1, Sua1, Sua1p, UBLE1A, Uble1a, uble1a, wu:fa28b04, zgc:86633

Protein level used designations for SAE1

  • SUMO-1 activating enzyme E1 N subunit
  • SUMO-1 activating enzyme subunit 1
  • SUMO-activating enzyme subunit 1
  • activator of SUMO1
  • sentrin/SUMO-activating protein AOS1
  • ubiquitin-like 1-activating enzyme E1A
  • ubiquitin-like protein SUMO-1 activating enzyme
  • ubiquitin-like (sentrin) activating enzyme E1A
  • ubiquitin-like 1 (sentrin) activating enzyme E1A
  • ubiquitin-like 1 (sentrin) activating enzyme subunit 1
  • SUMO-activating enzyme E1 N subunit
  • SUMO1 activating enzyme subunit 2a
  • Ubiquitin-like 1-activating enzyme E1A
  • fa28b04
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