Sclerostin Produits
(Sclerostin (SOST))
Catégories
Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008].
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Catégories Sclerostin en vedette
Sclerostin Anticorps
High quality antibodies with extensive validation data.
Sclerostin Kits ELISA
Reliable ELISA kits for a wide range of species.
Sclerostin Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Sclerostin recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (2)
- (5)
N° du produit
ABIN390193
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (1)
- (2)
N° du produit
ABIN7435190
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
N° du produit
ABIN7168635
Quantité
100 μL
Fiche technique
Fiche technique
Sclerostin recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
N° du produit
ABIN6959272
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
N° du produit
ABIN6959273
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
N° du produit
ABIN6959274
Quantité
96 tests
Fiche technique
Fiche technique
Sclerostin recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275636
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275637
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7275635
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Sclerostin
: "Targeting SOST using a small-molecule compound retards breast cancer bone metastasis." dans: Molecular cancer, Vol. 21, Issue 1, pp. 228, (2023) (PubMed).: "Significance of acPWV for Survival of Hemodialysis Patients." dans: Medicina (Kaunas, Lithuania), Vol. 56, Issue 9, (2020) (PubMed).
: "Evaluation of serum fibroblast growth factor-23 in patients with axial spondyloarthritis and its association with sclerostin, inflammation, and spinal damage." dans: Rheumatology international, Vol. 39, Issue 5, pp. 835-840, (2020) (PubMed).
: "Role of sclerostin and dkk1 in bone remodeling in type 2 diabetic patients." dans: Endocrine research, Vol. 43, Issue 1, pp. 29-38, (2018) (PubMed).
: "Co-expression of DKK-1 and Sclerostin in Subchondral Bone of the Proximal Femoral Heads from Osteoarthritic Hips." dans: Calcified tissue international, Vol. 100, Issue 6, pp. 609-618, (2018) (PubMed).
: "The effect of levetiracetam on rat bone mineral density, bone structure and biochemical markers of bone metabolism." dans: European journal of pharmacology, Vol. 824, pp. 115-119, (2018) (PubMed).
: "Sclerostin Promotes Bone Remodeling in the Process of Tooth Movement." dans: PLoS ONE, Vol. 12, Issue 1, pp. e0167312, (2017) (PubMed).
: "Upregulated serum sclerostin level in the T2DM patients with femur fracture inhibits the expression of bone formation/remodeling-associated biomarkers via antagonizing Wnt signaling." dans: European review for medical and pharmacological sciences, Vol. 21, Issue 3, pp. 470-478, (2017) (PubMed).
: "DMP-1-mediated Ghr gene recombination compromises skeletal development and impairs skeletal response to intermittent PTH." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 30, Issue 2, pp. 635-52, (2016) (PubMed).
: "Protection From Glucocorticoid-Induced Osteoporosis by Anti-Catabolic Signaling in the Absence of Sost/Sclerostin." dans: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 10, pp. 1791-1802, (2016) (PubMed).
Synonymes et noms alternatifs relatifs à Sclerostin
sclerostin (LOC100313724), sclerostin (SOST), sclerostin (Sost), 5430411E23Rik, CDD, LOC100313724, VBCHProtein level used designations for Sclerostin
- sclerostin
- sclerosteosis
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