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SCN7A Produits

(Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A))

Catégories

This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics\; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels\; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011].

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Catégories SCN7A en vedette

SCN7A Anticorps

High quality antibodies with extensive validation data.

SCN7A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, WB, IHC
Validations
  • (3)
N° du produit ABIN7169925
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IF
Validations
  • (1)
N° du produit ABIN7184122
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Rat
Application ELISA, IF (cc), IF (p), ICC, IHC (fro), IHC (p)
Validations
  • (1)
N° du produit ABIN1386696
Quantité 100 μL
Fiche technique Fiche technique

Dernières publications sur nos produits SCN7A

Gorter, Zurolo, Iyer, Fluiter, van Vliet, Baayen, Aronica: "Induction of sodium channel Na(x) (SCN7A) expression in rat and human hippocampus in temporal lobe epilepsy." dans: Epilepsia, Vol. 51, Issue 9, pp. 1791-800, (2010) (PubMed).

Synonymes et noms alternatifs relatifs à SCN7A

sodium channel, voltage-gated, type VII, alpha (Scn7a), sodium voltage-gated channel alpha subunit 7 (Scn7a), sodium voltage-gated channel alpha subunit 7 (SCN7A), 1110034K09Rik, AI642000, Na-G, NaG, Nav2, Nav2.1, Nav2.2, Nav2.3, Nax, Scn6a, SCN6A

Protein level used designations for SCN7A

  • sodium channel, voltage-gated, type VI, alpha polypeptide
  • sodium channel, voltage-gated, type VII, alpha polypeptide
  • sodium channel protein type 7 subunit alpha
  • sodium channel voltage-gated type VI alpha polypeptide
  • sodium channel, voltage-gated, type 6, alpha polypeptide
  • putative voltage-gated sodium channel subunit alpha Nax
  • sodium channel protein cardiac and skeletal muscle subunit alpha
  • sodium channel protein type VII subunit alpha
  • voltage-dependent sodium channel alpha subunit
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