Senataxin Produits
(Senataxin (SETX))
Catégories
This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4). [provided by RefSeq, Jul 2008].
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
Catégories Senataxin en vedette
Senataxin Anticorps
High quality antibodies with extensive validation data.
Senataxin Kits ELISA
Reliable ELISA kits for a wide range of species.
Senataxin recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (5)
N° du produit
ABIN565001
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
N° du produit
ABIN7164533
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC
Validations
- (1)
N° du produit
ABIN1385872
Quantité
100 μL
Fiche technique
Fiche technique
Senataxin recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Validations
N° du produit
ABIN1149655
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1149656
Quantité
96 tests
Fiche technique
Fiche technique
Senataxin recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1319693
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293T Cells
Validations
- (1)
N° du produit
ABIN2731631
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Senataxin
: "Sae2/CtIP prevents R-loop accumulation in eukaryotic cells." dans: eLife, Vol. 7, (2019) (PubMed).: "Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks." dans: Cell reports, Vol. 28, Issue 12, pp. 3167-3181.e6, (2019) (PubMed).
: "Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations." dans: Nature communications, Vol. 9, Issue 1, pp. 533, (2018) (PubMed).
: "A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links." dans: Nature communications, Vol. 9, Issue 1, pp. 2592, (2018) (PubMed).
: "Altered translational repression of an RNA-binding protein, Elav by AOA2-causative Senataxin mutation." dans: Synapse (New York, N.Y.), Vol. 71, Issue 5, (2017) (PubMed).
: "Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1." dans: Molecular cell, Vol. 65, Issue 5, pp. 832-847.e4, (2017) (PubMed).
: "SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination." dans: Nature, Vol. 529, Issue 7584, pp. 48-53, (2016) (PubMed).
: "A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage." dans: Genes & development, Vol. 27, Issue 20, pp. 2227-32, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à Senataxin
senataxin (SETX), senataxin (setx), senataxin (Setx), A130090N03, A930037J23Rik, ALS4, Als4, AOA2, AW060766, bA479K20.2, mKIAA0625, RGD1565575, SCAR1, Sen1, SETX, wu:fj92h09Protein level used designations for Senataxin
- senataxin
- amyotrophic lateral sclerosis 4
- probable helicase senataxin-like
- SEN1 homolog
- amyotrophic lateral sclerosis 4 protein
- probable helicase senataxin
- amyotrophic lateral sclerosis 4 homolog
- amyotrophic lateral sclerosis 4 protein homolog
- DEAxQ-box helicase
- tRNA splicing endonuclease regulator 1
Vous êtes ici:
