Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

SETD7 Produits

(SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories SETD7 en vedette

SETD7 Anticorps

High quality antibodies with extensive validation data.

SETD7 Kits ELISA

Reliable ELISA kits for a wide range of species.

SETD7 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SETD7 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Monkey, Rat
Application WB, ELISA, IHC, FACS, ICC, Neut
Validations
  • (5)
N° du produit ABIN7193393
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Monkey, Rat
Application WB, ELISA, IHC, FACS, ICC, Neut
Validations
  • (5)
N° du produit ABIN7193392
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), IF
Validations
  • (5)
N° du produit ABIN566461
Quantité 100 μg
Fiche technique Fiche technique

SETD7 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959453
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6951695
Quantité 96 tests
Fiche technique Fiche technique

SETD7 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1319680
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7504524
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3095428
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits SETD7

Zhao, Zhao, Gu, Yin, Shen, Tang, Xia, Zhang, Zhao, Yang, Zhang: "Minimally invasive implantation and decreased inflammation reduce osteoinduction of biomaterial." dans: Theranostics, Vol. 10, Issue 8, pp. 3533-3545, (2021) (PubMed).

Yin, Jia, Miron, Long, Xu, Wei, Wu, Zhang, Li: "Setd7 and its contribution to Boron-induced bone regeneration in Boron-mesoporous bioactive glass scaffolds." dans: Acta biomaterialia, Vol. 73, pp. 522-530, (2018) (PubMed).

Elkouris, Kontaki, Stavropoulos, Antonoglou, Nikolaou, Samiotaki, Szantai, Saviolaki, Brown, Sideras, Panayotou, Talianidis: "SET9-Mediated Regulation of TGF-β Signaling Links Protein Methylation to Pulmonary Fibrosis." dans: Cell reports, Vol. 15, Issue 12, pp. 2733-44, (2016) (PubMed).

Subramanian, Jia, Kapoor-Vazirani, Powell, Collins, Sharma, Peng, Cheng, Vertino: "Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase." dans: Molecular cell, Vol. 30, Issue 3, pp. 336-47, (2008) (PubMed).

Hotz, Peters: "Protein demethylation required for DNA methylation." dans: Nature genetics, Vol. 41, Issue 1, pp. 10-1, (2008) (PubMed).

Narayanan, Ruyechan, Kristie: "The coactivator host cell factor-1 mediates Set1 and MLL1 H3K4 trimethylation at herpesvirus immediate early promoters for initiation of infection." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 26, pp. 10835-40, (2007) (PubMed).

Chuikov, Kurash, Wilson, Xiao, Justin, Ivanov, McKinney, Tempst, Prives, Gamblin, Barlev, Reinberg: "Regulation of p53 activity through lysine methylation." dans: Nature, Vol. 432, Issue 7015, pp. 353-60, (2004) (PubMed).

Kwon, Chang, Kwak, Lee, Joachimiak, Kim, Lee, Cho: "Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet." dans: The EMBO journal, Vol. 22, Issue 2, pp. 292-303, (2003) (PubMed).

Xiao, Jing, Wilson, Walker, Vasisht, Kelly, Howell, Taylor, Blackburn, Gamblin: "Structure and catalytic mechanism of the human histone methyltransferase SET7/9." dans: Nature, Vol. 421, Issue 6923, pp. 652-6, (2003) (PubMed).

Wysocka, Myers, Laherty, Eisenman, Herr: "Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1." dans: Genes & development, Vol. 17, Issue 7, pp. 896-911, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à SETD7

SET domain containing lysine methyltransferase 7 (SETD7), SET domain containing (lysine methyltransferase) 7 (setd7), SET domain containing (lysine methyltransferase) 7 (Setd7), 1600028F23Rik, H3K4MT, KMT7, mKIAA1717, SET7, set7, Set7, SET7/9, Set7/9, SET9, zgc:92330, zgc:101860

Protein level used designations for SETD7

  • H3-K4-HMTase SETD7
  • SET domain-containing protein 7
  • histone H3-K4 methyltransferase SETD7
  • histone H3-lysine 4-specific methyltransferase
  • histone-lysine N-methyltransferase SETD7
  • lysine N-methyltransferase 7
  • H3-K4 methyltransferase
Vous êtes ici:
Support technique