Chèvre anti-Humain IgA (Free & Bound), (Secretory Component) Anticorps

N° du produit ABIN568608

Détail du produit

Antigène: IgA

Épitope: Free & Bound, Secretory Component

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Application: Immunodiffusion (ID), Immunoprecipitation (IP)

Purification: Serum

Immunogène: Secretory component is present in human secretions bound to secretory IgA (sIgA) and in free form. Secretory IgA (sIgA) functions as a dimer or polymer and accounts for almost all specific mucosal antibody activity. A molecule of sIgA is made up of two molecules of IgA, one J chain and one SC (MW 65,000). The dimer IgA is transported into secretions by its binding to the SC on the epithelial cells. Under normal conditions, sIgA contains both subclasses IgA1 and IgA2, since both are capable of binding SC. SC also has an affinity for polymeric IgM. Purified free human secretory component isolated from pooled milk is used for immunization. Freund's complete adjuvant is used in the first step of the immunization procedure.

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Restore by adding 0.5 mLsterile distilled water. Dilutions may be prepared by adding PBS, pH 7.2

Conseil sur la manipulation: Avoid repeated freezing and thawing.
Dilutions may be prepared by adding PBS, pH 7.2

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to and following reconstitution store the antibody at 2-8 °C for one month or at -28 °C for longer.

Détail du antigène

Antigène: IgA

Abstract: IgA Produits

Classe de substances: Antibody

Sujet: Synonyms: Human Immunoglobulin A