The antibody SC-05 reacts with 80 kDa human secretory component glycoprotein (both free and bound in secretory IgA). Recognized glycoprotein is specific membrane marker of glandular carcinomas.
Réactivité croisée (Details)
Human
Purification
Purified by protein-A affinity chromatography.
Pureté
> 95 % (by SDS-PAGE)
niveau d'endotoxine
Low Endotoxin
Immunogène
Affinity-purified secretory component from human colostrum.
Clone
SC-05
Isotype
IgG1
Indications d'application
Immunohistochemistry (frozen sections): Examples of positive human tissues: secretory mucosa of gastrointestinal and respiratory tract, epithelia of salivary glands, endometrium, endocervix, kidney, prostate, mammary gland. Recommended dilution: 2-8 μg/mL.
Restrictions
For Research Use only
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Do not freeze.
Stock
4 °C
Stockage commentaire
Store at 2-8°C. Do not freeze.
Bartek, Bartkova, Taylor-Papadimitriou: "Keratin 19 expression in the adult and developing human mammary gland." dans: The Histochemical journal, Vol. 22, Issue 10, pp. 537-44, (1991) (PubMed).
Kvale, Bartek, Sollid, Brandtzaeg: "Rapid selection of cultured cells with increased expression of a membrane marker (secretory component)." dans: International journal of cancer. Journal international du cancer, Vol. 42, Issue 4, pp. 638-41, (1988) (PubMed).