SGOL2 Produits
(Shugoshin-Like 2 (SGOL2))
Catégories
Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.
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Catégories SGOL2 en vedette
SGOL2 Anticorps
High quality antibodies with extensive validation data.
SGOL2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB
Validations
- (5)
- (1)
N° du produit
ABIN1881800
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
N° du produit
ABIN7188086
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
N° du produit
ABIN6287322
Quantité
50 μL
Fiche technique
Fiche technique
SGOL2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3095378
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3135963
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits SGOL2
: "The Ectopic Expression of Meiosis Regulatory Genes in Cutaneous T-Cell Lymphomas (CTCL)." dans: Frontiers in oncology, Vol. 9, pp. 429, (2019) (PubMed).: "Plk1 is upregulated in androgen-insensitive prostate cancer cells and its inhibition leads to necroptosis." dans: Oncogene, Vol. 32, Issue 24, pp. 2973-83, (2013) (PubMed).
: "Potential role of meiosis proteins in melanoma chromosomal instability." dans: Journal of skin cancer, Vol. 2013, pp. 190109, (2013) (PubMed).
: "Phosphorylation of mammalian Sgo2 by Aurora B recruits PP2A and MCAK to centromeres." dans: Genes & development, Vol. 24, Issue 19, pp. 2169-79, (2010) (PubMed).
: "Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy." dans: Nature genetics, Vol. 41, Issue 12, pp. 1345-9, (2009) (PubMed).
: "Unified mode of centromeric protection by shugoshin in mammalian oocytes and somatic cells." dans: Nature cell biology, Vol. 10, Issue 1, pp. 42-52, (2008) (PubMed).
: "Tripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachments." dans: The Journal of cell biology, Vol. 177, Issue 3, pp. 413-24, (2007) (PubMed).
: "Shugoshin collaborates with protein phosphatase 2A to protect cohesin." dans: Nature, Vol. 441, Issue 7089, pp. 46-52, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à SGOL2
shugoshin 2 (SGO2), shugoshin 2A (Sgo2a), 1110007N04Rik, 4932411A20Rik, 5730576N04Rik, AU018846, AV008062, D1Ertd8e, SGO2, TRIPIN, TripinProtein level used designations for SGOL2
- shugoshin-2
- shugoshin-like 2
- sgo2
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