SIA1 Protéines
(Siamois Homeodomain 1 (SIA1))
Essential for Wnt/beta-catenin-mediated formation of the Spemann organizer and for induction of the organizer precursor, the Nieuwkoop center. Acts as a transcriptional activator, cooperating with TGFbeta signals to induce a program of organizer- specific gene expression and to generate an organizer with both head- and trunk-inducing activity. Activates the head organizer gene cer1 by acting synergistically with otx2 and mix-A/mix.1 through the 5'-TAATCT-3' element of the cer1 promoter. Also binds as a complex with lhx1/lim1 and mix-A/mix.1 to the 3x 5'-TAAT-3' element of the cer1 promoter. Required for subsequent dorsoventral axis formation in the embryo, dorsalizing ventral mesoderm and cooperating with t/bra to induce dorsal mesoderm. Also involved in neural induction, inducing the cement gland and neural tissue in overlying ectoderm. Later in development, has the second function of indirectly repressing ventral genes, probably by activating the expression of a transcriptional repressor.
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
SIA1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Xenopus tropicalis
Source
Yeast
Validations
N° du produit
ABIN1620774
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Xenopus laevis
Source
Yeast
Validations
N° du produit
ABIN1642965
Quantité
1 mg
Fiche technique
Fiche technique
Synonymes et noms alternatifs relatifs à SIA1
siamois homeodomain 1 L homeolog (sia1.L), sia, siamois, siamois-A, XsiaProtein level used designations for SIA1
- Siamois homeo domain
- homeobox protein siamois
Vous êtes ici:
