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SIAH2 Produits

(Siah E3 Ubiquitin Protein Ligase 2 (SIAH2))
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. [provided by RefSeq, Jul 2008].

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Catégories SIAH2 en vedette

SIAH2 Anticorps

High quality antibodies with extensive validation data.

SIAH2 Kits ELISA

Reliable ELISA kits for a wide range of species.

SIAH2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SIAH2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
N° du produit ABIN6265080
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7151218
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
N° du produit ABIN652059
Quantité 400 μL
Fiche technique Fiche technique

SIAH2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1131322
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1131323
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1131324
Quantité 96 tests
Fiche technique Fiche technique

SIAH2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1319979
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1319977
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3095363
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits SIAH2

Ma, Cheng, Mu, Geng, Zhao, Luo, Ma, Chang, Liu, Gao, Nie, Xie, Han, Chen, Ma, Zhu, Chen: "The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression." dans: Nature communications, Vol. 10, Issue 1, pp. 1034, (2019) (PubMed).

Hughes, Hemenway, Guo, Yi, Yu, Hawley: "The E3 ubiquitin ligase Sina regulates the assembly and disassembly of the synaptonemal complex in Drosophila females." dans: PLoS genetics, Vol. 15, Issue 5, pp. e1008161, (2019) (PubMed).

Jing, Nguyen, Wang, Pascal, Guo, Xu, Ai, Deng, Masoodi, Yu, Zhang, Nelson, Xia, Wang: "DHX15 promotes prostate cancer progression by stimulating Siah2-mediated ubiquitination of androgen receptor." dans: Oncogene, Vol. 37, Issue 5, pp. 638-650, (2018) (PubMed).

Ma, Cheng, Gao, Mu, Chen, Wu, Chen, Zhu: "Zyxin-Siah2-Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathways." dans: Nature communications, Vol. 7, pp. 11123, (2016) (PubMed).

van der Willik, Timmermans, van Deurzen, Look, Reijm, van Zundert, Foekens, Trapman-Jansen, den Bakker, Westenend, Martens, Berns, Jansen: "SIAH2 protein expression in breast cancer is inversely related with ER status and outcome to tamoxifen therapy." dans: American journal of cancer research, Vol. 6, Issue 2, pp. 270-84, (2016) (PubMed).

van Reesema, Zheleva, Winston, Jansen, OConnor, Isbell, Bian, Qin, Bassett, Hinson, Dorsch, Kirby, Van Sciver, Tang-Tan, Harden, Chang, Allen, Perry, Hoefer, Tang: "SIAH and EGFR, Two RAS Pathway Biomarkers, are Highly Prognostic in Locally Advanced and Metastatic Breast Cancer." dans: EBioMedicine, Vol. 11, pp. 183-198, (2016) (PubMed).

Tanaka, Li, Urata, Goto, Ono, Kawakatsu, Matsushima, Hirabaru, Adachi, Kitasato, Takatsuki, Kuroki, Eguchi: "Increased expression of PHD3 represses the HIF-1 signaling pathway and contributes to poor neovascularization in pancreatic ductal adenocarcinoma." dans: Journal of gastroenterology, Vol. 50, Issue 9, pp. 975-83, (2015) (PubMed).

Qin, Smyrk, Reed, Schmidt, Schnelldorfer, Chari, Petersen, Tang: "Combining clinicopathological predictors and molecular biomarkers in the oncogenic K-RAS/Ki67/HIF-1α pathway to predict survival in resectable pancreatic cancer." dans: British journal of cancer, Vol. 112, Issue 3, pp. 514-22, (2015) (PubMed).

Moreno, Lara-Chica, Soler-Torronteras, Caro, Medina, Álvarez, Salvatierra, Muñoz, Calzado: "The Expression of the Ubiquitin Ligase SIAH2 (Seven In Absentia Homolog 2) Is Increased in Human Lung Cancer." dans: PLoS ONE, Vol. 10, Issue 11, pp. e0143376, (2015) (PubMed).

Wong, Chen, Liu, Parker, Möller: "Loss of Siah2 does not impact angiogenic potential of murine endothelial cells." dans: Microvascular research, Vol. 102, pp. 38-45, (2015) (PubMed).

Synonymes et noms alternatifs relatifs à SIAH2

siah E3 ubiquitin protein ligase 2 (SIAH2), siah E3 ubiquitin protein ligase 2 L homeolog (siah2.L), seven in absentia 2 (Siah2), siah E3 ubiquitin protein ligase 2 (Siah2), AA415433, hSiah2, siah2-A, Sinh2, Xsiah-2, xsiah2

Protein level used designations for SIAH2

  • E3 ubiquitin-protein ligase SIAH2
  • seven in absentia homolog 2
  • siah-2
  • seven in absentia-like protein
  • E3 ubiquitin-protein ligase siah2
  • mSiah2
  • seven in absentia 2
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