SIGMAR1 Produits
(sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
Catégories
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor\; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2008].
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Catégories SIGMAR1 en vedette
SIGMAR1 Anticorps
High quality antibodies with extensive validation data.
SIGMAR1 Kits ELISA
Reliable ELISA kits for a wide range of species.
SIGMAR1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SIGMAR1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, FACS
Validations
- (1)
- (3)
N° du produit
ABIN389221
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
N° du produit
ABIN7169599
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (2)
N° du produit
ABIN709841
Quantité
100 μL
Fiche technique
Fiche technique
SIGMAR1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Cow
Analytical Method
Quantitative
Validations
N° du produit
ABIN1058417
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Dog
Analytical Method
Quantitative
Validations
N° du produit
ABIN1058418
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Chicken
Analytical Method
Quantitative
Validations
N° du produit
ABIN1058419
Quantité
96 tests
Fiche technique
Fiche technique
SIGMAR1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1790001
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
N° du produit
ABIN7555502
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
N° du produit
ABIN7562503
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits SIGMAR1
: "Sigma-1 Receptor Antagonist (BD1047) Decreases Cathepsin B Secretion in HIV-Infected Macrophages Exposed to Cocaine." dans: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, (2018) (PubMed).: "TRPV1 channels and the progesterone receptor Sig-1R interact to regulate pain." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 7, pp. E1657-E1666, (2018) (PubMed).
: "The SigmaR1 chaperone drives breast and colorectal cancer cell migration by tuning SK3-dependent Ca2+ homeostasis. ..." dans: Oncogene, Vol. 36, Issue 25, pp. 3640-3647, (2017) (PubMed).
: "The sigma-1 receptors are present in monomeric and oligomeric forms in living cells in the presence and absence of ligands." dans: The Biochemical journal, Vol. 466, Issue 2, pp. 263-71, (2015) (PubMed).
: "Modeling tandem AAG8-MEK inhibition in melanoma cells." dans: Cancer medicine, Vol. 3, Issue 3, pp. 710-8, (2014) (PubMed).
: "Loss of function of the ALS protein SigR1 leads to ER pathology associated with defective autophagy and lipid raft disturbances." dans: Cell death & disease, Vol. 5, pp. e1290, (2014) (PubMed).
: "Sigma-1 receptor enhances neurite elongation of cerebellar granule neurons via TrkB signaling." dans: PLoS ONE, Vol. 8, Issue 10, pp. e75760, (2013) (PubMed).
: "Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis." dans: Human molecular genetics, Vol. 22, Issue 8, pp. 1581-600, (2013) (PubMed).
: "The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation." dans: The Journal of clinical investigation, Vol. 122, Issue 12, pp. 4569-79, (2012) (PubMed).
: "An unambiguous assay for the cloned human sigma1 receptor reveals high affinity interactions with dopamine D4 receptor selective compounds and a distinct structure-affinity relationship for ..." dans: European journal of pharmacology, Vol. 578, Issue 2-3, pp. 123-36, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à SIGMAR1
sigma non-opioid intracellular receptor 1 (SIGMAR1), sigma non-opioid intracellular receptor 1 (Sigmar1), sigma non-opioid intracellular receptor 1 L homeolog (sigmar1.L), sigma non-opioid intracellular receptor 1 (sigmar1), AL024364, ALS16, mSigmaR1, OPRS1, Oprs1, oprs1, SIG-1R, sigma1R, Sigma1R, SR-BP, SR-BP1, SRBP, zgc:56378Protein level used designations for SIGMAR1
- SR31747 binding protein 1
- aging-associated gene 8 protein
- hSigmaR1
- sigma 1-type opioid receptor
- opioid receptor, sigma 1
- sigma1-receptor
- sigma1R
- Sigma 1-type opioid receptor
- Sigma1-receptor
- sigma1-receptor (sterol-isomerase like protein)
- sterol isomerase-like protein
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